Protein: NEK10
Serine/threonine-protein kinase Nek10 (EC 2.7.11.1) (Never in mitosis A-related kinase 10) (NimA-related protein kinase 10)

Gene: NEK10
Organism: Homo sapiens
Interactions: 172
UniProt ID: Q6ZWH5

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005576 - extracellular region
GO:0006468 - protein phosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

74039

MYO9A
Unconventional myosin-IXa

1

10

High-throughput

0.691

High

1115751

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

19

High-throughput

0.691

High

1098803

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

16

Small-scale

0.647

High

95973

E7EU96
Casein kinase II subunit alpha

1

20

High-throughput

0.575

High

258953

DNJA2
DnaJ homolog subfamily A member 2

1

8

High-throughput

0.575

High

573539

ENPL
Endoplasmin

1

20

High-throughput

0.575

High

1038646

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

14

High-throughput

0.575

High

1117394

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

10

High-throughput

0.575

High

1144279

STK38
Serine/threonine-protein kinase 38

1

14

High-throughput

0.575

High

91679

C9JGE3
RNA-binding protein EWS

1

8

High-throughput

0.514

High

95943

E7ET15
U2 snRNP-associated SURP motif-containing protein

1

4

High-throughput

0.514

High

104397

F5H823
RAP1B, member of RAS oncogene family

1

10

High-throughput

0.514

High

114445

H0Y6E7
RNA binding motif protein X-linked

1

8

High-throughput

0.514

High

116304

H3BPG5
RNA-binding protein with serine-rich domain 1

1

1

High-throughput

0.514

High

117276

K7ELV6
Cold-inducible RNA-binding protein

1

4

High-throughput

0.514

High

172135

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

13

High-throughput

0.514

High

290946

PPM1B
Protein phosphatase 1B

1

18

High-throughput

0.514

High

471870

RU2B
U2 small nuclear ribonucleoprotein B''

1

9

High-throughput

0.514

High

472838

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

4

High-throughput

0.514

High

550337

PABP1
Polyadenylate-binding protein 1

1

2

High-throughput

0.514

High

775162

FUS
RNA-binding protein FUS

1

7

High-throughput

0.514

High

910560

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

6

High-throughput

0.514

High

1023255

RBM3
RNA-binding protein 3

1

8

High-throughput

0.514

High

1061031

SRSF1
Serine/arginine-rich splicing factor 1

1

9

High-throughput

0.514

High

1062024

SRSF4
Serine/arginine-rich splicing factor 4

1

9

High-throughput

0.514

High

1096343

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

14

High-throughput

0.514

High

1099131

SRSF5
Serine/arginine-rich splicing factor 5

1

10

High-throughput

0.514

High

1099406

SRSF6
Serine/arginine-rich splicing factor 6

1

12

High-throughput

0.514

High

1111799

TRA2A
Transformer-2 protein homolog alpha

1

5

High-throughput

0.514

High

1124984

RCN2
Reticulocalbin-2

1

20

High-throughput

0.514

High

1140251

IF4H
Eukaryotic translation initiation factor 4H

1

7

High-throughput

0.514

High

1154858

NEDD8
Ubiquitin-like protein NEDD8

1

6

High-throughput

0.514

High

1257224

DNJC9
DnaJ homolog subfamily C member 9

1

5

High-throughput

0.514

High

1257234

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

10

High-throughput

0.514

High

415668

HSPB1
Heat shock protein beta-1

1

8

High-throughput

0.494

High

914283

EFNA4
Ephrin-A4

1

1

High-throughput

0.479

High

76500

B4DY91
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

1

11

High-throughput

0.445

High

95960

E7ETR0
RuvB-like helicase

1

5

High-throughput

0.445

High

107023

F8VPD4
Multifunctional protein CAD

1

2

High-throughput

0.445

High

130141

PGRC1
Membrane-associated progesterone receptor component 1

1

1

High-throughput

0.445

High

229740

CALU
Calumenin

1

16

High-throughput

0.445

High

359679

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

High-throughput

0.445

High

407478

K2C1
Keratin, type II cytoskeletal 1

1

3

High-throughput

0.445

High

446159

PYGL
Glycogen phosphorylase, liver form

1

2

High-throughput

0.445

High

476160

ANXA5
Annexin A5

1

5

High-throughput

0.445

High

528281

THIO
Thioredoxin

1

6

High-throughput

0.445

High

532700

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.445

High

539198

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

6

High-throughput

0.445

High

608642

DDX5
Probable ATP-dependent RNA helicase DDX5

1

5

High-throughput

0.445

High

697156

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.445

High

717316

PEBP1
Phosphatidylethanolamine-binding protein 1

1

3

High-throughput

0.445

High

801383

HSPA9
Stress-70 protein, mitochondrial

1

18

High-throughput

0.445

High

894562

GDIB
Rab GDP dissociation inhibitor beta

1

2

High-throughput

0.445

High

994273

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

20

High-throughput

0.445

High

1062522

DHX9
ATP-dependent RNA helicase A

1

6

High-throughput

0.445

High

1130084

SMC1A
Structural maintenance of chromosomes protein 1A

1

7

High-throughput

0.445

High

1134247

IMB1
Importin subunit beta-1

1

5

High-throughput

0.445

High

1156122

ZYX
Zyxin

1

1

High-throughput

0.445

High

1214712

ATD3B
ATPase family AAA domain-containing protein 3B

1

10

High-throughput

0.445

High

1257225

DDX17
Probable ATP-dependent RNA helicase DDX17

1

5

High-throughput

0.445

High

1257231

ATD3A
ATPase family AAA domain-containing protein 3A

1

8

High-throughput

0.445

High

1257239

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

4

Small-scale

0.437

High

459899

APT
Adenine phosphoribosyltransferase

1

0

High-throughput

0.426

High

71042

A8MUD9
Large ribosomal subunit protein uL30

1

5

High-throughput

0.407

High

76639

B4E022
transketolase

1

6

High-throughput

0.407

High

91557

C9J3N8
Heat shock protein family B

1

5

High-throughput

0.407

High

91817

C9JQV0
Chromosome 7 open reading frame 50

1

2

High-throughput

0.407

High

91878

C9JXB8
Large ribosomal subunit protein eL24

1

2

High-throughput

0.407

High

91896

C9K025
Large ribosomal subunit protein eL33

1

1

High-throughput

0.407

High

94362

D6RA26
Pleiotropic regulator 1

1

2

High-throughput

0.407

High

97044

E9PLL6
Large ribosomal subunit protein uL15

1

1

High-throughput

0.407

High

99221

F2Z388
Large ribosomal subunit protein uL29

1

1

High-throughput

0.407

High

107348

F8VXI7
Dynein light chain LC8-type 1

1

7

High-throughput

0.407

High

108014

G3V1A4
Cofilin 1

1

5

High-throughput

0.407

High

109331

G5E972
Thymopoietin

1

7

High-throughput

0.407

High

109543

G5E9G0
Large ribosomal subunit protein uL3

1

2

High-throughput

0.407

High

114605

H0YKT8
Proteasome subunit beta

1

8

High-throughput

0.407

High

116919

J3KMX5
Small ribosomal subunit protein uS15

1

1

High-throughput

0.407

High

117140

J3QSV6
Ribosomal L1 domain-containing protein 1

1

4

High-throughput

0.407

High

117141

J3QT28
Mitotic checkpoint protein BUB3

1

10

High-throughput

0.407

High

117799

M0QZG7
Small nuclear ribonucleoprotein polypeptide A

1

4

High-throughput

0.407

High

256902

H2B1K
Histone H2B type 1-K

1

13

High-throughput

0.407

High

279807

CISY
Citrate synthase, mitochondrial

1

1

High-throughput

0.407

High

367596

CAH2
Carbonic anhydrase 2

1

1

High-throughput

0.407

High

408088

TBB4A
Tubulin beta-4A chain

1

11

High-throughput

0.407

High

408951

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

5

High-throughput

0.407

High

428176

RLA1
Large ribosomal subunit protein P1

1

2

High-throughput

0.407

High

447142

NPM
Nucleophosmin

1

2

High-throughput

0.407

High

488503

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

5

High-throughput

0.407

High

538981

EPB41
Protein 4.1

1

10

High-throughput

0.407

High

551117

PCNA
Proliferating cell nuclear antigen

1

5

High-throughput

0.407

High

566174

K1C10
Keratin, type I cytoskeletal 10

1

7

High-throughput

0.407

High

567431

TCTP
Translationally-controlled tumor protein

1

1

High-throughput

0.407

High

592854

CBR1
Carbonyl reductase [NADPH] 1

1

2

High-throughput

0.407

High

617537

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

1

High-throughput

0.407

High

656165

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

2

High-throughput

0.407

High

658248

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.407

High

673902

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.407

High

686225

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.407

High

691160

1433T
14-3-3 protein theta

1

20

High-throughput

0.407

High

693805

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.407

High

729984

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.407

High

731408

STIP1
Stress-induced-phosphoprotein 1

1

12

High-throughput

0.407

High

846355

MATR3
Matrin-3

1

4

High-throughput

0.407

High

855894

CRKL
Crk-like protein

1

10

High-throughput

0.407

High

861200

MAP1B
Microtubule-associated protein 1B

1

8

High-throughput

0.407

High

880328

RL34
Large ribosomal subunit protein eL34

1

1

High-throughput

0.407

High

895924

F10A1
Hsc70-interacting protein

1

20

High-throughput

0.407

High

914643

RM12
Large ribosomal subunit protein bL12m

1

2

High-throughput

0.407

High

926194

ICLN
Methylosome subunit pICln

1

1

High-throughput

0.407

High

933673

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

4

High-throughput

0.407

High

961322

RL27
Large ribosomal subunit protein eL27

1

1

High-throughput

0.407

High

961759

RL37A
Large ribosomal subunit protein eL43

1

2

High-throughput

0.407

High

966511

1433G
14-3-3 protein gamma

1

20

High-throughput

0.407

High

969931

RS16
Small ribosomal subunit protein uS9

1

3

High-throughput

0.407

High

971687

1433E
14-3-3 protein epsilon

1

20

High-throughput

0.407

High

972716

RS23
Small ribosomal subunit protein uS12

1

2

High-throughput

0.407

High

974412

SMD1
Small nuclear ribonucleoprotein Sm D1

1

4

High-throughput

0.407

High

974772

SMD3
Small nuclear ribonucleoprotein Sm D3

1

4

High-throughput

0.407

High

979021

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.407

High

981868

RL23
Large ribosomal subunit protein uL14

1

1

High-throughput

0.407

High

982712

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.407

High

1026103

CLH1
Clathrin heavy chain 1

1

3

High-throughput

0.407

High

1049465

1433F
14-3-3 protein eta

1

20

High-throughput

0.407

High

1057190

PRDX1
Peroxiredoxin-1

1

6

High-throughput

0.407

High

1057780

RL18
Large ribosomal subunit protein eL18

1

1

High-throughput

0.407

High

1058480

CKAP4
Cytoskeleton-associated protein 4

1

7

High-throughput

0.407

High

1097375

CBX3
Chromobox protein homolog 3

1

1

High-throughput

0.407

High

1138333

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

7

High-throughput

0.407

High

1148300

CNN3
Calponin-3

1

4

High-throughput

0.407

High

1152120

MARE1
Microtubule-associated protein RP/EB family member 1

1

4

High-throughput

0.407

High

1204912

Q5HYB6
Epididymis luminal protein 189

1

12

High-throughput

0.407

High

1250065

CASPC
Inactive caspase-12

1

5

High-throughput

0.407

High

1257223

Q8WVC2
40S ribosomal protein S21

1

3

High-throughput

0.407

High

1257226

RANB9
Ran-binding protein 9

1

5

High-throughput

0.407

High

1257232

GID8
Glucose-induced degradation protein 8 homolog

1

2

High-throughput

0.407

High

1257236

AKP8L
A-kinase anchor protein 8-like

1

1

High-throughput

0.407

High

1257237

RTRAF
RNA transcription, translation and transport factor protein

1

1

High-throughput

0.407

High

1257238

COF2
Cofilin-2

1

5

High-throughput

0.407

High

1257240

SERC
Phosphoserine aminotransferase

1

1

High-throughput

0.407

High

1257241

S4R359
Heterogeneous nuclear ribonucleoprotein K

1

9

High-throughput

0.407

High

1257235

PFD2
Prefoldin subunit 2

2

0

High-throughput

0.313

High

182150

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.279

Low

261829

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.279

Low

963316

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.279

Low

1257227

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.279

Low

1257228

TALD3
Protein TALPID3

1

0

High-throughput

0.279

Low

1257230

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.279

Low

91729

C9JL85
Myotrophin

1

0

High-throughput

0.232

Low

94361

D6R9V8
CDV3 homolog

1

0

High-throughput

0.232

Low

94452

D6RC60
Nucleolar protein 16

1

0

High-throughput

0.232

Low

95808

E5RI99
Large ribosomal subunit protein eL30

1

0

High-throughput

0.232

Low

95815

E5RIW3
Tubulin-specific chaperone A

1

0

High-throughput

0.232

Low

95872

E7EPB3
Large ribosomal subunit protein eL14

1

0

High-throughput

0.232

Low

107350

F8VY02
Endoplasmic reticulum resident protein 29

1

0

High-throughput

0.232

Low

107419

F8W895
G patch domain-containing protein 4

1

0

High-throughput

0.232

Low

108056

G3V302
MYC associated factor X

1

0

High-throughput

0.232

Low

109555

G5E9R5
acid phosphatase

1

0

High-throughput

0.232

Low

116483

H7BZW6
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.232

Low

116818

I6L8B7
Fatty acid binding protein 5

1

0

High-throughput

0.232

Low

117067

J3KTF8
Rho GDP-dissociation inhibitor 1

1

0

High-throughput

0.232

Low

117835

M0R2L9
Ribosomal protein S19

1

0

High-throughput

0.232

Low

162356

PDCD5
Programmed cell death protein 5

1

0

High-throughput

0.232

Low

298011

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.232

Low

405301

OAT
Ornithine aminotransferase, mitochondrial

1

0

High-throughput

0.232

Low

480200

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.232

Low

751329

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

1

0

High-throughput

0.232

Low

860809

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.232

Low

983300

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.232

Low

1039263

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.232

Low

1257229

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

High-throughput

0.232

Low

1257233

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025