Interactor 1: GLYC (P34896)
Serine hydroxymethyltransferase, cytosolic (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)
Gene: SHMT1

Interactor 2: GLYM (P34897)
Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)
Gene: SHMT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SHMT~SHMT
Common GO terms GO:0004372 - glycine hydroxymethyltransferase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0006544 - glycine metabolic process
GO:0006563 - L-serine metabolic process
and 11 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 483
Hs

1 504
+ Hs
+ Hs
+ Sp
+ At
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024