Interactor 1: NOT4 (P34909)
General negative regulator of transcription subunit 4 (EC 2.3.2.27) (Modulator of transcription 2)
Gene: MOT2

Interactor 2: CAF40 (P53829)
Protein CAF40 (40 kDa CCR4-associated factor)
Gene: CAF40

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.758

The method score is based on:

Property Details
Experiments 11733989, 17965252, 27851962, 17513889, 19155328, 20386698, 28180299, 30948432, 32299921, 19707589, 37968396, 21406554, 18467557, 16926149
Identification Methods coimmunoprecipitation, two hybrid, affinity chromatography technology, biochemical, dihydrofolate reductase reconstruction, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0005634 - nucleus
GO:0030015 - CCR4-NOT core complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 587
Sc

1 373
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024