HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: BARD1 (Q99728)
BRCA1-associated RING domain protein 1 (BARD-1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BARD1)
Gene: BARD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26022179
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 840 Hs			1 777
+	Hs
		714269 HSP74_HUMAN (1-840): 0: 993: 100.00		BCOR_HUMAN (152-543): 1.16e-44: 176: 23.93
+	Hs
		714414 HSP74_HUMAN (1-840): 0: 993: 100.00		Q9H4D1_HUMAN (216-431): 1.1e-17: 90: 8.04
+	Hs
		714162 HSP74_HUMAN (1-840): 0: 993: 100.00		RIPK4_HUMAN (216-431): 2.07e-17: 89.2: 7.59
+	Mm
		821834 HS74L_MOUSE (1-840): 0: 962: 61.91		ANS1B_MOUSE (217-465): 1.28e-26: 118: 12.11
+	Hs
		276146 HSP74_HUMAN (1-840): 0: 993: 100.00		PSD10_HUMAN (272-468): 6e-18: 85.3: 11.94
+	Hs
		320911 HS74L_HUMAN (1-840): 0: 959: 63.21		Q9H4D1_HUMAN (216-431): 1.1e-17: 90: 8.04
+	Hs
		320835 HS74L_HUMAN (1-840): 0: 959: 63.21		RIPK4_HUMAN (216-431): 2.07e-17: 89.2: 7.59
+	Sc
		694838 HSP7F_YEAST (5-697): 5.7e-137: 424: 37.61		HOS4_YEAST (373-528): 3.59e-13: 75.5: 38.27
+	Hs
		503916 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		ANK2_HUMAN (104-622): 2.47e-71: 257: 14.31
+	Hs
		483759 HS71A_HUMAN (571-686): 1.59e-19: 95.5: 23.93		ANK2_HUMAN (104-622): 2.47e-71: 257: 14.31
+	Hs
		504362 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		ANKH1_HUMAN (114-664): 2.01e-66: 242: 14.16
+	Hs
		714021 HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48		ANKK1_HUMAN (100-553): 2.37e-66: 236: 14.38
+	Hs
		504758 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		Q9H4D1_HUMAN (216-431): 1.1e-17: 90: 8.04
+	Hs
		503777 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		RIPK4_HUMAN (216-431): 2.07e-17: 89.2: 7.59
+	Hs
		276135 HS71A_HUMAN (571-686): 1.59e-19: 95.5: 23.93		PSD10_HUMAN (272-468): 6e-18: 85.3: 11.94
+	Hs
		564185 HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86		Q9H4D1_HUMAN (216-431): 1.1e-17: 90: 8.04
+	Hs
		564048 HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86		RIPK4_HUMAN (216-431): 2.07e-17: 89.2: 7.59