HitPredict - High confidence protein-protein interactions

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	24072822, 22328140, 23273993
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex and 16 others more... GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008284 - positive regulation of cell population proliferation GO:0009410 - response to xenobiotic stimulus GO:0010628 - positive regulation of gene expression GO:0016525 - negative regulation of angiogenesis GO:0019899 - enzyme binding GO:0019901 - protein kinase binding GO:0031625 - ubiquitin protein ligase binding GO:0033234 - negative regulation of protein sumoylation GO:0043066 - negative regulation of apoptotic process GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0098978 - glutamatergic synapse GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1	781
Hs

1	551

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Last updated: 15 Jul 2024