Protein: TEAD2
Transcriptional enhancer factor TEF-4 (TEA domain family member 2) (TEAD-2)

Gene: TEAD2
Organism: Homo sapiens
Interactions: 126
UniProt ID: Q15562

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001223 - transcription coactivator binding
GO:0001570 - vasculogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

862161

YAP1
Transcriptional coactivator YAP1

10

20

Small-scale

0.977

High

1150192

TEAD4
Transcriptional enhancer factor TEF-3

4

6

High-throughput

0.892

High

1150248

VGLL1
Transcription cofactor vestigial-like protein 1

3

11

Small-scale

0.845

High

703146

TEAD1
Transcriptional enhancer factor TEF-1

2

6

High-throughput

0.811

High

71109

VGLL3
Transcription cofactor vestigial-like protein 3

2

12

High-throughput

0.783

High

1121006

VGLL4
Transcription cofactor vestigial-like protein 4

2

4

High-throughput

0.783

High

1150228

TEAD2
Transcriptional enhancer factor TEF-4

2

6

High-throughput

0.755

High

1150252

WWTR1
WW domain-containing transcription regulator protein 1

5

19

High-throughput

0.721

High

926664

HIRA
Protein HIRA

2

2

High-throughput

0.628

High

1150238

UBN2
Ubinuclein-2

2

3

High-throughput

0.628

High

279048

TRIM3
Tripartite motif-containing protein 3

3

4

High-throughput

0.607

High

1029842

RUNX1
Runt-related transcription factor 1

2

1

High-throughput

0.606

High

1150274

SP16H
FACT complex subunit SPT16

2

0

High-throughput

0.602

High

1150231

USF2
Upstream stimulatory factor 2

1

2

High-throughput

0.573

High

1150235

B2L15
Bcl-2-like protein 15

1

0

High-throughput

0.561

High

173704

BTAF1
TATA-binding protein-associated factor 172

1

8

High-throughput

0.536

High

177463

ZN536
Zinc finger protein 536

1

3

High-throughput

0.536

High

243646

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

7

High-throughput

0.536

High

245628

ZEB2
Zinc finger E-box-binding homeobox 2

1

2

High-throughput

0.536

High

277698

H2AY
Core histone macro-H2A.1

1

1

High-throughput

0.536

High

336224

ZIC2
Zinc finger protein ZIC 2

1

2

High-throughput

0.536

High

340891

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

3

High-throughput

0.536

High

404076

GCR
Glucocorticoid receptor

1

3

High-throughput

0.536

High

478907

PO2F2
POU domain, class 2, transcription factor 2

1

6

High-throughput

0.536

High

522820

COT1
COUP transcription factor 1

1

2

High-throughput

0.536

High

576231

PO2F1
POU domain, class 2, transcription factor 1

1

5

High-throughput

0.536

High

617165

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

4

High-throughput

0.536

High

665100

COT2
COUP transcription factor 2

1

1

High-throughput

0.536

High

703324

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

7

High-throughput

0.536

High

904759

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.536

High

1029684

FOXK2
Forkhead box protein K2

1

2

High-throughput

0.536

High

1032758

SATB1
DNA-binding protein SATB1

1

3

High-throughput

0.536

High

1094681

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.536

High

1094765

CAF1B
Chromatin assembly factor 1 subunit B

1

2

High-throughput

0.536

High

1098299

TBX2
T-box transcription factor TBX2

1

2

High-throughput

0.536

High

1129315

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

3

High-throughput

0.536

High

1130052

SMC1A
Structural maintenance of chromosomes protein 1A

1

3

High-throughput

0.536

High

1132714

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

5

High-throughput

0.536

High

1150239

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

2

High-throughput

0.536

High

1150240

ZFHX4
Zinc finger homeobox protein 4

1

2

High-throughput

0.536

High

1150242

CHD1L
Chromodomain-helicase-DNA-binding protein 1-like

1

5

High-throughput

0.536

High

1150243

ARI3B
AT-rich interactive domain-containing protein 3B

1

8

High-throughput

0.536

High

1150246

HXB13
Homeobox protein Hox-B13

1

8

High-throughput

0.536

High

1150256

BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A

1

2

High-throughput

0.536

High

1150258

HELLS
Lymphoid-specific helicase

1

8

High-throughput

0.536

High

1150260

SALL1
Sal-like protein 1

1

1

High-throughput

0.536

High

1150263

SMAL1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1

1

10

High-throughput

0.536

High

1150264

H2AW
Core histone macro-H2A.2

1

1

High-throughput

0.536

High

1150268

TRPS1
Zinc finger transcription factor Trps1

1

1

High-throughput

0.536

High

1150272

SATB2
DNA-binding protein SATB2

1

3

High-throughput

0.536

High

1150273

SMC3
Structural maintenance of chromosomes protein 3

1

3

High-throughput

0.536

High

1150229

NCOA1
Nuclear receptor coactivator 1

1

3

Small-scale

0.527

High

123107

DX39A
ATP-dependent RNA helicase DDX39A

1

0

High-throughput

0.513

High

231482

ORC4
Origin recognition complex subunit 4

1

0

High-throughput

0.513

High

519510

MYBB
Myb-related protein B

1

0

High-throughput

0.513

High

652319

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

0

High-throughput

0.513

High

718572

CDC27
Cell division cycle protein 27 homolog

1

0

High-throughput

0.513

High

770001

RFC1
Replication factor C subunit 1

1

0

High-throughput

0.513

High

854860

RECQ1
ATP-dependent DNA helicase Q1

1

0

High-throughput

0.513

High

907442

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.513

High

939887

DLX5
Homeobox protein DLX-5

1

0

High-throughput

0.513

High

1086223

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.513

High

1104344

ORC2
Origin recognition complex subunit 2

1

0

High-throughput

0.513

High

1132606

KIF22
Kinesin-like protein KIF22

1

0

High-throughput

0.513

High

1146370

LRC41
Leucine-rich repeat-containing protein 41

1

0

High-throughput

0.513

High

1150233

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

0

High-throughput

0.513

High

1150236

LIN9
Protein lin-9 homolog

1

0

High-throughput

0.513

High

1150237

INT3
Integrator complex subunit 3

1

0

High-throughput

0.513

High

1150241

CASZ1
Zinc finger protein castor homolog 1

1

0

High-throughput

0.513

High

1150249

DCNL5
DCN1-like protein 5

1

0

High-throughput

0.513

High

1150253

ADNP
Activity-dependent neuroprotector homeobox protein

1

0

High-throughput

0.513

High

1150255

ZBT20
Zinc finger and BTB domain-containing protein 20

1

0

High-throughput

0.513

High

1150266

ORC3
Origin recognition complex subunit 3

1

0

High-throughput

0.513

High

1150267

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

1

0

High-throughput

0.513

High

1150270

RALY
RNA-binding protein Raly

1

0

High-throughput

0.513

High

170154

AURKA
Aurora kinase A

1

1

High-throughput

0.501

High

372112

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.501

High

400880

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.501

High

474006

NFIC
Nuclear factor 1 C-type

1

7

High-throughput

0.501

High

549161

CDK4
Cyclin-dependent kinase 4

1

1

High-throughput

0.501

High

693322

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

1

High-throughput

0.501

High

710258

EPHA2
Ephrin type-A receptor 2

1

2

High-throughput

0.501

High

728254

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

High-throughput

0.501

High

833579

SOX3
Transcription factor SOX-3

1

5

High-throughput

0.501

High

842766

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

3

High-throughput

0.501

High

842918

CDN2B
Cyclin-dependent kinase 4 inhibitor B

1

1

High-throughput

0.501

High

858660

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

3

High-throughput

0.501

High

861617

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

2

High-throughput

0.501

High

1025353

CDK6
Cyclin-dependent kinase 6

1

1

High-throughput

0.501

High

1097094

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

1

3

High-throughput

0.501

High

1150232

HIF1A
Hypoxia-inducible factor 1-alpha

1

1

High-throughput

0.501

High

1150245

GLIS1
Zinc finger protein GLIS1

1

2

High-throughput

0.501

High

1150247

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

2

High-throughput

0.501

High

1150250

NSD3
Histone-lysine N-methyltransferase NSD3

1

1

High-throughput

0.501

High

1150251

GLIS2
Zinc finger protein GLIS2

1

2

High-throughput

0.501

High

1150257

LATS2
Serine/threonine-protein kinase LATS2

1

3

High-throughput

0.501

High

1150269

DACH1
Dachshund homolog 1

1

1

High-throughput

0.501

High

1124816

FLOT2
Flotillin-2

1

2

High-throughput

0.500

High

162943

TERT
Telomerase reverse transcriptase

1

0

High-throughput

0.480

High

413895

P53
Cellular tumor antigen p53

1

0

High-throughput

0.480

High

571194

HGF
Hepatocyte growth factor

1

0

High-throughput

0.480

High

718818

CCND2
G1/S-specific cyclin-D2

1

0

High-throughput

0.480

High

1126687

BECN1
Beclin-1

1

0

High-throughput

0.480

High

1150230

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.480

High

1150259

RASF1
Ras association domain-containing protein 1

1

0

High-throughput

0.480

High

1150271

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.480

High

385774

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

4

High-throughput

0.479

High

461508

HS90A
Heat shock protein HSP 90-alpha

1

1

High-throughput

0.479

High

468401

HS90B
Heat shock protein HSP 90-beta

1

1

High-throughput

0.479

High

604819

HXB9
Homeobox protein Hox-B9

1

5

High-throughput

0.479

High

724933

HXA10
Homeobox protein Hox-A10

1

7

High-throughput

0.479

High

771590

HXD13
Homeobox protein Hox-D13

1

11

High-throughput

0.479

High

1150254

NANOG
Homeobox protein NANOG

1

3

High-throughput

0.479

High

616324

RCC1
Regulator of chromosome condensation

1

0

High-throughput

0.458

High

648522

FGFR4
Fibroblast growth factor receptor 4

1

1

High-throughput

0.457

High

299207

FLOT1
Flotillin-1

1

2

High-throughput

0.457

High

725181

HXC13
Homeobox protein Hox-C13

1

10

High-throughput

0.445

High

1150234

HS904
Putative heat shock protein HSP 90-alpha A4

1

2

High-throughput

0.407

High

1128979

I5P1
Inositol polyphosphate-5-phosphatase A

2

0

High-throughput

0.316

High

1150244

S6OS1
Protein SIX6OS1

2

0

High-throughput

0.316

High

1150265

GBG13

2

0

High-throughput

0.316

High

515919

SAA2
Serum amyloid A-2 protein

1

0

High-throughput

0.292

High

1150261

ABCF3
ATP-binding cassette sub-family F member 3

1

0

High-throughput

0.279

Low

1150262

NSMA3
Sphingomyelin phosphodiesterase 4

1

0

High-throughput

0.279

Low

76529

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025