HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: ACTA (P62736)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: ACTA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34316702
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 377
+	Hs
		717670 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Mm
		1206351 RING2_MOUSE (7-227): 5.77e-50: 171: 16.61		ACTBL_MOUSE (4-377): 0: 721: 89.04
+	Hs
		584915 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		584922 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		ACTA_HUMAN (1-377): 0: 596: 100.00
+	Hs
		891732 TRI26_HUMAN (5-210): 1e-49: 175: 16.59		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		933049 TRIM6_HUMAN (5-189): 2.83e-49: 173: 16.67		ACTS_HUMAN (1-377): 0: 598: 97.88
+	Mm
		892212 RING2_MOUSE (7-227): 5.77e-50: 171: 16.61		ACTB_MOUSE (4-377): 0: 598: 94.12
+	Mm
		929807 RING2_MOUSE (7-227): 5.77e-50: 171: 16.61		ACTG_MOUSE (4-377): 0: 598: 94.39
+	Hs
		929977 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Hs
		930096 TRIM6_HUMAN (5-189): 2.83e-49: 173: 16.67		ACTH_HUMAN (4-377): 0: 591: 99.20
+	Hs
		282592 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		ACTB_HUMAN (4-377): 0: 598: 94.12