HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 2364
+	Hs
		718187 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN4_HUMAN (5-2092): 2.42e-155: 540: 52.21
+	Hs
		282627 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		SPTB2_HUMAN (1-2364): 0: 751: 100.00
+	Hs
		963368 DTX3_HUMAN (17-62): 3.98e-10: 62.2: 39.13		SPTB2_HUMAN (1-2364): 0: 751: 100.00
+	Hs
		521481 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		ACTN1_HUMAN (28-775): 4.31e-92: 323: 34.25
+	Hs
		718225 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN5_HUMAN (532-2342): 1.97e-37: 158: 12.52
+	Hs
		211495 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		ACTN4_HUMAN (53-525): 6.51e-121: 409: 47.58
+	Hs
		717728 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00
+	Hs
		513833 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		DMD_HUMAN (234-2093): 2.37e-21: 105: 9.67
+	Hs
		717799 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		717542 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		UTRN_HUMAN (212-2073): 1e-17: 93.2: 10.02
+	Hs
		717848 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59
+	Hs
		718318 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MACF1_HUMAN (687-1920): 4.98e-16: 87.6: 12.23
+	Hs
		164573 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10
+	Hs
		521464 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		ACTN1_HUMAN (28-775): 4.31e-92: 323: 34.25
+	Hs
		282506 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		ACTN1_HUMAN (28-775): 4.31e-92: 323: 34.25
+	Hs
		584968 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		PLEC_HUMAN (222-1144): 1.08e-16: 89.7: 11.59
+	Hs
		282645 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89