HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 325
+	Hs
		196962 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67
+	Hs
		717626 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		718351 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15
+	Hs
		1032142 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00
+	Hs
		282641 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00
+	Dm
		1279331 Q9VV77_DROME (3-229): 2.77e-68: 214: 36.80		EBI_DROME (4-177): 1.25e-42: 157: 15.22
+	Hs
		903492 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Mm
		903677 RING2_MOUSE (7-227): 5.77e-50: 171: 16.61		WDR5_MOUSE (180-325): 1.26e-38: 141: 15.65
+	Hs
		903455 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		903159 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		585027 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		282600 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65
+	Hs
		1019346 TRI26_HUMAN (5-210): 1e-49: 175: 16.59		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		1281338 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		135035 TRI38_HUMAN (1-203): 9.11e-44: 158: 16.51		FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05
+	Hs
		282755 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15