HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21430439
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 605
+	Hs
		585096 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		585092 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		209398 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47
+	Hs
		717626 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		196962 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PRP4_HUMAN (387-594): 6.19e-35: 140: 23.66
+	Hs
		585027 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		1019346 TRI26_HUMAN (5-210): 1e-49: 175: 16.59		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		1281338 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		135035 TRI38_HUMAN (1-203): 9.11e-44: 158: 16.51		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		903492 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Mm
		903677 RING2_MOUSE (7-227): 5.77e-50: 171: 16.61		WDR5_MOUSE (458-605): 5.01e-38: 145: 25.33
+	Hs
		903455 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Dm
		1279331 Q9VV77_DROME (3-229): 2.77e-68: 214: 36.80		EBI_DROME (500-605): 2.04e-16: 85: 18.42
+	Hs
		903159 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Mm
		1206589 RING2_MOUSE (7-227): 5.77e-50: 171: 16.61		TBL1R_MOUSE (501-605): 5.38e-15: 80: 16.67
+	Hs
		1304089 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		TBL1R_HUMAN (501-605): 3.85e-15: 80.4: 16.67
+	Hs
		282600 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33