HitPredict

Interactor 1: NOS2 (P35228)
Nitric oxide synthase, inducible (EC 1.14.13.39) (Hepatocyte NOS) (HEP-NOS) (Inducible NO synthase) (Inducible NOS) (iNOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)
Gene: NOS2

Interactor 2: SPSB2 (Q99619)
SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9)
Gene: SPSB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.741

Property	Details
Experiments	20603330, 28549582, 33862200, 21199876, 21549100, 23438482
Identification Methods	enzymatic study, x-ray crystallography, pull down, unspecified method, affinity chromatography technology
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1153 Hs			1 263
+	Hs
		718523 NOS2_HUMAN (1-1153): 0: 1800: 100.00		SPSB1_HUMAN (1-263): 3.24e-121: 348: 50.55
+	Hs
		718522 NOS2_HUMAN (1-1153): 0: 1800: 100.00		SPSB4_HUMAN (1-263): 1.62e-114: 331: 50.92
+	Hs
		472681 NOS2_HUMAN (1-1153): 0: 1800: 100.00		FBSP1_HUMAN (28-220): 9.54e-75: 230: 42.27
+	Hs
		718518 NOS2_HUMAN (1-1153): 0: 1800: 100.00		TRI67_HUMAN (47-222): 5.66e-39: 146: 19.13
+	Hs
		718513 NOS2_HUMAN (1-1153): 0: 1800: 100.00		HERC1_HUMAN (59-209): 1.51e-27: 113: 19.21
+	Hs
		560208 NCPR_HUMAN (502-1128): 0: 749: 29.78		TRI67_HUMAN (47-222): 5.66e-39: 146: 19.13
+	Hs
		1172144 NDOR1_HUMAN (536-1129): 0: 580: 26.71		TRI67_HUMAN (47-222): 5.66e-39: 146: 19.13