HitPredict

Interactor 1: PHB1 (P35232)
Prohibitin 1
Gene: PHB1

Interactor 2: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	19377303
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0019899 - enzyme binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 904
+	Hs
		832664 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		MCM2_HUMAN (1-904): 0: 1078: 100.00
+	Hs
		708388 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		MCM4_HUMAN (2-885): 0: 847: 28.42
+	Hs
		708561 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		MCM5_HUMAN (169-902): 0: 768: 29.43
+	Hs
		708742 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		MCM5_HUMAN (169-902): 0: 768: 29.43
+	Hs
		627197 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		MCM3_HUMAN (186-897): 0: 725: 29.20
+	Hs
		718857 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		MCM6_HUMAN (186-817): 0: 710: 31.18
+	Hs
		708818 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		MCM7_HUMAN (188-886): 0: 707: 27.35