HitPredict

Interactor 1: B3KSH4 (B3KSH4)
Huntingtin interacting protein 2, isoform CRA_a (cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa)
Gene: HIP2

Interactor 2: BIRC8 (Q96P09)
Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis)
Gene: BIRC8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19549727
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 97 Hs			1 236
+	Hs
		896357 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		BIRC8_HUMAN (1-236): 1.07e-86: 258: 100.00
+	Hs
		896319 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		Q6PIA0_HUMAN (1-236): 2.73e-86: 257: 99.15
+	Hs
		919831 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		BIRC8_HUMAN (1-236): 1.07e-86: 258: 100.00
+	Hs
		896349 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		BIRC7_HUMAN (1-236): 4.79e-61: 195: 33.47
+	Hs
		72150 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		BIRC7_HUMAN (1-236): 4.79e-61: 195: 33.47
+	Hs
		919817 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		BIRC7_HUMAN (1-236): 4.79e-61: 195: 33.47
+	Hs
		919813 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		MIB2_HUMAN (37-234): 9.33e-29: 115: 19.34
+	Hs
		919804 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RFFL_HUMAN (64-236): 4.82e-24: 100: 17.78
+	At
		715121 UBC8_ARATH (1-52): 1.23e-29: 104: 38.46		RGLG3_ARATH (53-234): 4.34e-24: 100: 15.61
+	At
		715118 UBC8_ARATH (1-52): 1.23e-29: 104: 38.46		LUL3_ARATH (86-233): 1.1e-23: 99.3: 17.76
+	Hs
		919809 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RNF34_HUMAN (161-236): 2.91e-23: 98: 36.84
+	Hs
		919803 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		MYLIP_HUMAN (166-235): 7.52e-21: 92.2: 35.71
+	Dm
		639392 UBCD1_DROME (1-51): 1.57e-29: 104: 39.22		DIAP1_DROME (4-84): 6.4e-19: 86.6: 32.93
+	Hs
		919721 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		BIRC3_HUMAN (4-158): 5.42e-18: 84.3: 24.20
+	Hs
		895787 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		BIRC3_HUMAN (4-158): 5.42e-18: 84.3: 24.20
+	Hs
		919722 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		BIRC2_HUMAN (4-148): 2.85e-16: 79.3: 24.49
+	Hs
		895788 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		BIRC2_HUMAN (4-148): 2.85e-16: 79.3: 24.49
+	Hs
		919707 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		XIAP_HUMAN (3-211): 1.12e-13: 71.6: 15.07
+	Hs
		895777 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		XIAP_HUMAN (3-211): 1.12e-13: 71.6: 15.07
+	Hs
		919776 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		MIB1_HUMAN (158-233): 9.18e-12: 66: 25.00