Interactor 1: IRS1 (P35569)
Insulin receptor substrate 1 (IRS-1)
Gene: IRS1

Interactor 2: TRI72 (Q1XH17)
Tripartite motif-containing protein 72 (Mitsugumin-53) (Mg53)
Gene: Trim72

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 23354051
Identification Methods anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0046627 - negative regulation of insulin receptor signaling pathway
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1233
Mm

1 477
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024