Interactor 1: ACRB (P31224)
Multidrug efflux pump subunit AcrB (AcrAB-TolC multidrug efflux pump subunit AcrB) (Acridine resistance protein B)
Gene: ACRB

Interactor 2: MDTF (P37637)
Multidrug resistance protein MdtF
Gene: MDTF

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16858726
Identification Methods blue native page
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ACR_tran~ACR_tran
Common GO terms GO:0005886 - plasma membrane
GO:0009636 - response to toxic substance
GO:0015125 - bile acid transmembrane transporter activity
GO:0015562 - efflux transmembrane transporter activity
GO:0015721 - bile acid and bile salt transport
and 4 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1049
Ec

1 1037
+ Ec
+ Pa
+ Ec
+ Ec
+ Ec
+ Ec
+ Bs
+ Bs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025