HitPredict

Interactor 1: MYH9 (P35579)
Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA)
Gene: MYH9

Interactor 2: CEP89 (Q96ST8)
Centrosomal protein of 89 kDa (Cep89) (Centrosomal protein 123) (Cep123) (Coiled-coil domain-containing protein 123)
Gene: CEP89

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1960 Hs			1 783
+	Hs
		724686 MYH9_HUMAN (1-1923): 0: 1124: 100.00		MYH9_HUMAN (268-774): 1.96e-23: 109: 12.33
+	Hs
		724943 MYH9_HUMAN (1-1923): 0: 1124: 100.00		MY18A_HUMAN (39-550): 9.2e-17: 87.5: 10.73
+	Hs
		148460 MYH9_HUMAN (1-1923): 0: 1124: 100.00		CTRO_HUMAN (73-685): 3.76e-13: 75.8: 12.74
+	Hs
		725035 MYH9_HUMAN (1-1923): 0: 1124: 100.00		MYO5C_HUMAN (258-750): 2.4e-11: 69.7: 13.37
+	Hs
		724687 MYH9_HUMAN (1-1923): 0: 1124: 100.00		MYH10_HUMAN (451-777): 3.75e-11: 69.4: 10.61
+	Hs
		528356 MYH6_HUMAN (979-1960): 2.36e-62: 239: 16.84		MYH6_HUMAN (321-774): 1.81e-18: 92.9: 11.65
+	Dm
		1303379 MYSN_DROME (938-1959): 1.1e-59: 230: 16.51		MYSN_DROME (274-782): 1.25e-17: 90.2: 12.09
+	Hs
		528432 MYH13_HUMAN (916-1960): 3.35e-66: 251: 17.46		MYH8_HUMAN (497-773): 3.58e-10: 65.9: 10.47
+	Ce
		361110 MYO3_CAEEL (938-1960): 3.59e-62: 238: 16.25		MYO4_CAEEL (194-755): 9.42e-14: 77.8: 12.31
+	Rn
		361106 MYH6_RAT (979-1960): 9.02e-62: 237: 16.62		MYH6_RAT (45-503): 1.84e-13: 76.7: 10.24
+	Hs
		502901 MYH6_HUMAN (979-1960): 2.36e-62: 239: 16.84		MYH3_HUMAN (38-512): 4.58e-12: 72.1: 10.46
+	Hs
		148466 MYH11_HUMAN (723-1800): 1.94e-59: 229: 16.27		CTRO_HUMAN (73-685): 3.76e-13: 75.8: 12.74
+	Hs
		502933 MYH3_HUMAN (1063-1960): 8.04e-58: 224: 17.96		MYH4_HUMAN (35-465): 2.2e-13: 76.3: 10.88
+	Hs
		725097 MYH11_HUMAN (723-1800): 1.94e-59: 229: 16.27		MYH10_HUMAN (451-777): 3.75e-11: 69.4: 10.61
+	Hs
		522657 MYH4_HUMAN (1185-1960): 9.21e-49: 194: 14.34		MYH7_HUMAN (253-782): 3.21e-20: 98.6: 11.28
+	Ce
		361109 MYO4_CAEEL (730-1729): 1.73e-53: 209: 16.65		MYO4_CAEEL (194-755): 9.42e-14: 77.8: 12.31
+	Hs
		528435 MYH8_HUMAN (1260-1959): 2.25e-50: 199: 16.76		MYH4_HUMAN (35-465): 2.2e-13: 76.3: 10.88