HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: EF1A1 (P68104)
Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)
Gene: EEF1A1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25192599
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 462
+	Hs
		932920 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		EF1A1_HUMAN (1-462): 0: 578: 100.00
+	Sc
		367579 PABP_YEAST (263-381): 1.57e-10: 65.5: 18.49		EF1A_YEAST (1-445): 0: 538: 80.90
+	Hs
		545927 RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35		ERF3A_HUMAN (2-443): 3.59e-162: 469: 37.47
+	Hs
		545846 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		ERF3A_HUMAN (2-443): 3.59e-162: 469: 37.47
+	Hs
		1119139 PAP1L_HUMAN (182-382): 2.39e-13: 74.7: 13.43		ERF3B_HUMAN (2-443): 1.29e-159: 467: 36.12
+	Hs
		1031386 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		ERF3B_HUMAN (2-443): 1.29e-159: 467: 36.12
+	Hs
		516347 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		ERF3A_HUMAN (2-443): 3.59e-162: 469: 37.47
+	Hs
		516584 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		ERF3B_HUMAN (2-443): 1.29e-159: 467: 36.12