HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: KHDR1 (Q07666)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: KHDRBS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	29884807, 35271311, 27460707
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 443
+	Hs
		967127 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		267483 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		KHDR3_HUMAN (100-443): 1.37e-128: 377: 56.46
+	Hs
		967224 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62
+	Hs
		967370 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		QKI_HUMAN (93-367): 1.56e-92: 284: 33.89
+	Hs
		1075712 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33
+	Hs
		726844 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33
+	Hs
		967199 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33
+	Hs
		1075774 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33
+	Sc
		376973 PABP_YEAST (263-381): 1.57e-10: 65.5: 18.49		BBP_YEAST (75-284): 1.31e-50: 180: 21.33