HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: SMU1 (Q2TAY7)
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]
Gene: SMU1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29884807
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0008380 - RNA splicing
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 513
+	Hs
		1103006 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		SMU1_HUMAN (1-513): 7.53e-153: 447: 100.00
+	Hs
		903407 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		726698 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		903140 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		903196 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		516438 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		1271160 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		726980 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		967471 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		NLE1_HUMAN (433-513): 1.02e-23: 106: 23.46
+	Hs
		967341 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		1288389 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		212170 HTSF1_HUMAN (267-372): 6.19e-23: 104: 21.30		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		929746 RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35		RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33
+	Hs
		929439 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33
+	Hs
		516453 PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44		RACK1_HUMAN (277-377): 7.24e-11: 65.5: 33.33