HitPredict

Interactor 1: NU214 (P35658)
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)
Gene: NUP214

Interactor 2: NXF2 (Q9GZY0)
Nuclear RNA export factor 2 (Cancer/testis antigen 39) (CT39) (TAP-like protein 2) (TAPL-2)
Gene: NXF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	11073998, 28514442, 33961781
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006406 - mRNA export from nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2090 Hs			1 626
+	Hs
		727326 NU214_HUMAN (1-2090): 0: 691: 100.00		NXF1_HUMAN (14-622): 0: 880: 58.92
+	Hs
		858064 NUP98_HUMAN (1481-1973): 9.16e-17: 89.7: 15.60		NXF1_HUMAN (14-622): 0: 880: 58.92
+	Hs
		1017095 TROP_HUMAN (1690-2090): 6.16e-09: 63.9: 20.34		NXF2_HUMAN (1-626): 0: 881: 100.00
+	Mm
		1307775 MAP1A_MOUSE (415-1323): 4.39e-10: 67.6: 9.66		NXF1_MOUSE (14-622): 0: 870: 57.05
+	Dm
		1353486 NU214_DROME (13-1800): 1.5e-63: 242: 15.11		NXF1_DROME (41-622): 0: 539: 25.80
+	Mm
		1246890 MAP1A_MOUSE (415-1323): 4.39e-10: 67.6: 9.66		Q8R499_MOUSE (6-623): 0: 666: 42.59
+	Sc
		971930 NU116_YEAST (1635-2087): 1.93e-21: 104: 19.54		MEX67_YEAST (125-624): 4.94e-113: 352: 18.89
+	Tt
		101905 NU145_CHATD (1121-1948): 5.4e-17: 90.2: 14.65		G0SET4_CHATD (25-622): 2.9e-112: 352: 21.59
+	Sc
		830687 NU145_YEAST (1481-1847): 6.54e-16: 86.7: 15.82		MEX67_YEAST (125-624): 4.94e-113: 352: 18.89
+	Sc
		971886 NU100_YEAST (1215-1810): 7.25e-11: 69.8: 13.32		MEX67_YEAST (125-624): 4.94e-113: 352: 18.89