Protein: PDK2
[Pyruvate dehydrogenase (acetyl-transferring)] kinase 2, mitochondrial (PDK 2) (Pyruvate dehydrogenase kinase 2) (EC 2.7.11.2) (Protein kinase of PDH protein 2) (Pyruvate dehydrogenase complex kinase 2) (PDC kinase 2) ([Pyruvate dehydrogenase [lipoamide]] kinase 2)

Gene: PDK2, PKP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 99
UniProt ID: P53170

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004740 - pyruvate dehydrogenase (acetyl-transferring) kinase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

775145

PDK1
[Pyruvate dehydrogenase

3

11

Small-scale

0.855

High

366625

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.501

High

389120

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

3

High-throughput

0.501

High

409665

KAPC
cAMP-dependent protein kinase type 3

1

7

High-throughput

0.501

High

412815

KAPA
cAMP-dependent protein kinase type 1

1

8

High-throughput

0.501

High

413003

KAPB
cAMP-dependent protein kinase type 2

1

7

High-throughput

0.501

High

608798

KCC2
Calcium/calmodulin-dependent protein kinase II

1

3

High-throughput

0.501

High

659876

PRR1
Serine/threonine-protein kinase PRR1

1

1

High-throughput

0.501

High

692571

ZUO1
Zuotin

1

2

High-throughput

0.501

High

730486

NNK1
Nitrogen network kinase 1

1

2

High-throughput

0.501

High

743462

YPK3
Serine/threonine-protein kinase YPK3

1

5

High-throughput

0.501

High

743904

AKL1
Serine/threonine-protein kinase AKL1

1

1

High-throughput

0.501

High

752163

KSP1
Serine/threonine-protein kinase KSP1

1

4

High-throughput

0.501

High

755726

TOM71
Protein TOM71

1

3

High-throughput

0.501

High

767338

ICP55
Intermediate cleaving peptidase 55

1

1

High-throughput

0.501

High

774934

MAM33
Mitochondrial acidic protein MAM33

1

2

High-throughput

0.501

High

859080

ATG1
Serine/threonine-protein kinase ATG1

1

1

High-throughput

0.501

High

562990

STF2
ATPase-stabilizing factor 15 kDa protein

1

0

High-throughput

0.480

High

598602

UTR1
NAD(+) kinase

1

0

High-throughput

0.480

High

617238

MBR1
Mitochondrial biogenesis regulation protein 1

1

0

High-throughput

0.480

High

688911

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.480

High

699798

KPR1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.480

High

744215

MAK5
ATP-dependent RNA helicase MAK5

1

0

High-throughput

0.480

High

772623

YJH0
Inactive deaminase YJL070C

1

0

High-throughput

0.480

High

773699

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.480

High

811885

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

0

High-throughput

0.480

High

859870

MTM1
Mitochondrial carrier protein MTM1

1

0

High-throughput

0.480

High

859871

YG5L
Uncharacterized protein YGR266W

1

0

High-throughput

0.480

High

859898

FMP16
Protein FMP16, mitochondrial

1

0

High-throughput

0.480

High

478369

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.479

High

705453

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.479

High

826146

TOM22
Mitochondrial import receptor subunit TOM22

1

1

High-throughput

0.479

High

357331

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

532797

ACOX
Acyl-coenzyme A oxidase

1

7

High-throughput

0.457

High

579962

DAP2
Dipeptidyl aminopeptidase B

1

1

High-throughput

0.457

High

648328

GYS2
Glycogen [starch] synthase isoform 2

1

1

High-throughput

0.457

High

685417

MLF3
Protein MLF3

1

1

High-throughput

0.457

High

707035

MSN4
Zinc finger protein MSN4

1

1

High-throughput

0.457

High

728083

MNR2
Manganese resistance protein MNR2

1

1

High-throughput

0.457

High

770317

RUXG
Small nuclear ribonucleoprotein G

1

2

High-throughput

0.457

High

774170

VHS2
Protein VHS2

1

1

High-throughput

0.457

High

797004

ALR2
Magnesium transporter ALR2

1

1

High-throughput

0.457

High

858787

MGA1
Protein MGA1

1

1

High-throughput

0.457

High

859881

SNX41
Sorting nexin-41

1

1

High-throughput

0.457

High

859888

FRA1
Putative Xaa-Pro aminopeptidase FRA1

1

1

High-throughput

0.457

High

859877

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.438

High

540197

NMT
Glycylpeptide N-tetradecanoyltransferase

1

0

High-throughput

0.261

Low

576178

SPO7
Sporulation-specific protein SPO7

1

0

High-throughput

0.261

Low

613728

RS3A2
Small ribosomal subunit protein eS1B

1

0

High-throughput

0.261

Low

622053

SSD1
Protein SSD1

1

0

High-throughput

0.261

Low

627654

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.261

Low

659182

LAC1
Ceramide synthase LAC1

1

0

High-throughput

0.261

Low

677531

MLS1
Malate synthase 1

1

0

High-throughput

0.261

Low

693442

PAH1
Phosphatidic acid phosphohydrolase 1

1

0

High-throughput

0.261

Low

693866

SRP40
Suppressor protein SRP40

1

0

High-throughput

0.261

Low

704467

RE104
Meiotic recombination protein REC104

1

0

High-throughput

0.261

Low

707240

NPL4
Nuclear protein localization protein 4

1

0

High-throughput

0.261

Low

712966

BMH2
Protein BMH2

1

0

High-throughput

0.261

Low

734141

PXL1
Paxillin-like protein 1

1

0

High-throughput

0.261

Low

734164

SKG1
Suppressor of lethality of KEX2 GAS1 double null mutant protein 1

1

0

High-throughput

0.261

Low

740831

SOL2
6-phosphogluconolactonase-like protein 2

1

0

High-throughput

0.261

Low

742727

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.261

Low

747760

ICS2
Increased copper sensitivity protein 2

1

0

High-throughput

0.261

Low

755514

YPT35
Endosomal/vacuolar adapter protein YPT35

1

0

High-throughput

0.261

Low

756485

ADY1
Prospore formation at selected spindle poles protein 1

1

0

High-throughput

0.261

Low

757098

SET5
Histone-lysine N-methyltransferase SET5

1

0

High-throughput

0.261

Low

770378

SIP5
Protein SIP5

1

0

High-throughput

0.261

Low

783860

AZF1
Transcription factor AZF1

1

0

High-throughput

0.261

Low

783880

BUD6
Bud site selection protein 6

1

0

High-throughput

0.261

Low

797778

IGD1
Inhibitor of glycogen debranching 1

1

0

High-throughput

0.261

Low

805050

ARC1
tRNA-aminoacylation cofactor ARC1

1

0

High-throughput

0.261

Low

810667

ALY2
Arrestin-related trafficking adapter 3

1

0

High-throughput

0.261

Low

811523

AVT1
Vacuolar amino acid transporter 1

1

0

High-throughput

0.261

Low

847971

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.261

Low

859868

ORM1
Protein ORM1

1

0

High-throughput

0.261

Low

859869

CENPQ
Inner kinetochore subunit OKP1

1

0

High-throughput

0.261

Low

859872

ZRG17
Protein ZRG17

1

0

High-throughput

0.261

Low

859873

YIF1
Protein transport protein YIF1

1

0

High-throughput

0.261

Low

859874

CWC25
Pre-mRNA-splicing factor CWC25

1

0

High-throughput

0.261

Low

859875

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

0

High-throughput

0.261

Low

859876

DOS2
Protein DOS2

1

0

High-throughput

0.261

Low

859878

LCL1
Long chronological lifespan protein 1

1

0

High-throughput

0.261

Low

859879

YP077
Uncharacterized protein YPL077C

1

0

High-throughput

0.261

Low

859880

YD042
Uncharacterized protein YDR042C

1

0

High-throughput

0.261

Low

859882

SEG1
Eisosome protein SEG1

1

0

High-throughput

0.261

Low

859883

YM54
Uncharacterized protein YMR196W

1

0

High-throughput

0.261

Low

859884

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.261

Low

859886

HBT1
Protein HBT1

1

0

High-throughput

0.261

Low

859887

TPO1
Polyamine transporter 1

1

0

High-throughput

0.261

Low

859889

ENT4
Epsin-4

1

0

High-throughput

0.261

Low

859890

CMS1
Protein CMS1

1

0

High-throughput

0.261

Low

859891

NBA1
Protein NBA1

1

0

High-throughput

0.261

Low

859892

ALG6
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase

1

0

High-throughput

0.261

Low

859893

BAG7
Rho-GTPase-activating protein BAG7

1

0

High-throughput

0.261

Low

859894

NPC1
NPC intracellular sterol transporter 1-related protein 1

1

0

High-throughput

0.261

Low

859895

SCM3
Protein SCM3

1

0

High-throughput

0.261

Low

859896

WHI5
G1-specific transcriptional repressor WHI5

1

0

High-throughput

0.261

Low

859897

OSH2
Oxysterol-binding protein homolog 2

1

0

High-throughput

0.261

Low

859885

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024