HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: IQCB1 (Q15051)
IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ)
Gene: IQCB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21565611
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 639 Hs			1 598
+	Mm
		1112091 K22E_MOUSE (150-515): 0: 595: 81.69		IQCB1_MOUSE (1-598): 0: 1069: 86.96
+	Mm
		376399 K2C1_MOUSE (147-498): 7.89e-169: 498: 68.75		IQCB1_MOUSE (1-598): 0: 1069: 86.96
+	Mm
		1152730 K2C1B_MOUSE (143-495): 6.51e-169: 495: 70.54		IQCB1_MOUSE (1-598): 0: 1069: 86.96
+	Hs
		409078 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		IQCB1_HUMAN (1-598): 0: 1065: 100.00
+	Hs
		380616 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		IQCB1_HUMAN (1-598): 0: 1065: 100.00
+	Mm
		1152722 Q6IFT3_MOUSE (72-628): 6.71e-91: 300: 42.22		IQCB1_MOUSE (1-598): 0: 1069: 86.96
+	Mm
		1157154 K2C73_MOUSE (1-598): 7.34e-84: 275: 48.83		IQCB1_MOUSE (1-598): 0: 1069: 86.96
+	Mm
		1152850 K2C72_MOUSE (1-563): 2.26e-81: 267: 48.49		IQCB1_MOUSE (1-598): 0: 1069: 86.96
+	Hs
		531576 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		IQCB1_HUMAN (1-598): 0: 1065: 100.00
+	Hs
		380479 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		IQCB1_HUMAN (1-598): 0: 1065: 100.00
+	Hs
		821661 K2C6C_HUMAN (5-510): 2.02e-81: 269: 61.61		IQCB1_HUMAN (1-598): 0: 1065: 100.00
+	Mm
		1113324 K22O_MOUSE (1-604): 5.15e-78: 261: 54.79		IQCB1_MOUSE (1-598): 0: 1069: 86.96
+	Mm
		1206956 K2C5_MOUSE (1-506): 7.46e-78: 260: 59.22		IQCB1_MOUSE (1-598): 0: 1069: 86.96
+	Hs
		359495 K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22		IQCB1_HUMAN (1-598): 0: 1065: 100.00
+	Hs
		1065949 K2C74_HUMAN (1-563): 1.33e-76: 255: 51.69		IQCB1_HUMAN (1-598): 0: 1065: 100.00