HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	31006538, 33545068, 20562859
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 639 Hs			1 125
+	Hs
		380685 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		380691 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		380586 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		305888 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		380687 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		318881 K2C75_HUMAN (1-582): 6e-90: 291: 53.58		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		318887 K2C75_HUMAN (1-582): 6e-90: 291: 53.58		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		318792 K2C75_HUMAN (1-582): 6e-90: 291: 53.58		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		305879 K2C75_HUMAN (1-582): 6e-90: 291: 53.58		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		318883 K2C75_HUMAN (1-582): 6e-90: 291: 53.58		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		891073 KRT85_HUMAN (5-491): 4.47e-87: 282: 45.59		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306103 KRT85_HUMAN (5-491): 4.47e-87: 282: 45.59		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		531627 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		531633 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		531546 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		380455 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		305939 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		306027 K2C6C_HUMAN (5-510): 2.02e-81: 269: 61.61		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		531629 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		380519 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46