HitPredict

Interactor 1: VGFR3 (P35916)
Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)
Gene: FLT4

Interactor 2: PFKAP (Q01813)
ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase)
Gene: PFKP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1363 Hs			1 784
+	Hs
		572623 VGFR1_HUMAN (19-1342): 0: 828: 38.63		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		452393 PGFRB_HUMAN (19-555): 1.14e-123: 413: 22.80		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		437721 FLT3_HUMAN (837-1217): 1.41e-97: 338: 45.98		PFKAM_HUMAN (13-779): 0: 1030: 71.78
+	Hs
		571681 VGFR3_HUMAN (1-1363): 0: 982: 100.00		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		607944 FGFR4_HUMAN (535-810): 1.64e-14: 80.8: 15.79		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		507955 FGFR1_HUMAN (2-160): 6.17e-14: 78.9: 11.93		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Hs
		601497 FGFR2_HUMAN (2-160): 1e-11: 71.9: 14.12		PFKAP_HUMAN (1-784): 0: 1093: 100.00
+	Mm
		519479 PTK7_MOUSE (2-154): 5.42e-17: 89.3: 13.55		PFKAL_MOUSE (19-779): 0: 1023: 69.42
+	Hs
		571663 VGFR1_HUMAN (19-1342): 0: 828: 38.63		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		571682 FLT3_HUMAN (837-1217): 1.41e-97: 338: 45.98		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03
+	Hs
		571668 FGFR3_HUMAN (310-670): 4.9e-27: 121: 13.53		PFKAL_HUMAN (396-739): 1.72e-65: 234: 27.03