Interactor 1: VGFR3 (P35917)
Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)
Gene: Flt4

Interactor 2: VEGFC (P97953)
Vascular endothelial growth factor C (VEGF-C) (Flt4 ligand) (Flt4-L) (Vascular endothelial growth factor-related protein) (VRP)
Gene: VEGFC

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 9012504
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ig_3~PDGF
Common GO terms GO:0001525 - angiogenesis
GO:0001934 - positive regulation of protein phosphorylation
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0002040 - sprouting angiogenesis
GO:0008284 - positive regulation of cell population proliferation
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1363
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1 415
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Last updated: 15 Jul 2024