HitPredict

Interactor 1: FMR1 (P35922)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1) (mFmr1p)
Gene: FMR1

Interactor 2: ELAV2 (Q60899)
ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Mel-N1)
Gene: Elavl2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28671696
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0045202 - synapse GO:1990904 - ribonucleoprotein complex
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 614 Mm			1 360
+	Mm
		729493 FMR1_MOUSE (1-614): 0: 1011: 100.00		ELAV4_MOUSE (1-360): 1.13e-94: 288: 84.18
+	Mm
		729487 FMR1_MOUSE (1-614): 0: 1011: 100.00		ELAV3_MOUSE (1-360): 3.33e-90: 276: 76.29
+	Hs
		516477 FMR1_HUMAN (1-614): 0: 995: 93.99		PABP1_HUMAN (22-298): 1.28e-43: 161: 20.34
+	Hs
		668344 FMR1_HUMAN (1-614): 0: 995: 93.99		RBMS1_HUMAN (37-227): 9.01e-27: 111: 36.55
+	Mm
		729447 FMR1_MOUSE (1-614): 0: 1011: 100.00		ELAV1_MOUSE (262-358): 1.86e-20: 92.4: 24.74
+	Mm
		1141834 FXR1_MOUSE (1-334): 0: 589: 73.65		ELAV2_MOUSE (1-360): 1.82e-100: 302: 100.00
+	Mm
		1142832 FXR1_MOUSE (1-334): 0: 589: 73.65		ELAV4_MOUSE (1-360): 1.13e-94: 288: 84.18
+	Hs
		843649 FXR1_HUMAN (1-334): 0: 596: 73.95		PABP4_HUMAN (122-359): 5.08e-43: 159: 18.80
+	Mm
		665753 FXR1_MOUSE (1-334): 0: 589: 73.65		PABP1_MOUSE (22-298): 1.2e-43: 161: 20.34
+	Hs
		668328 FXR1_HUMAN (1-334): 0: 596: 73.95		RBMS1_HUMAN (37-227): 9.01e-27: 111: 36.55
+	Mm
		936677 FXR1_MOUSE (1-334): 0: 589: 73.65		ELAV1_MOUSE (262-358): 1.86e-20: 92.4: 24.74
+	Mm
		1141837 Q8BPK8_MOUSE (268-399): 9.61e-11: 65.9: 16.91		ELAV2_MOUSE (1-360): 1.82e-100: 302: 100.00
+	Mm
		1143076 Q8BPK8_MOUSE (268-399): 9.61e-11: 65.9: 16.91		ELAV4_MOUSE (1-360): 1.13e-94: 288: 84.18
+	Mm
		1141840 Q8BPK8_MOUSE (268-399): 9.61e-11: 65.9: 16.91		ELAV3_MOUSE (1-360): 3.33e-90: 276: 76.29
+	Hs
		668329 FXR2_HUMAN (268-524): 2.3e-57: 206: 32.72		RBMS1_HUMAN (37-227): 9.01e-27: 111: 36.55
+	Mm
		936690 Q8BPK8_MOUSE (268-399): 9.61e-11: 65.9: 16.91		ELAV1_MOUSE (262-358): 1.86e-20: 92.4: 24.74