HitPredict

Interactor 1: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR

Interactor 2: EPN1 (Q9Y6I3)
Epsin-1 (EH domain-binding mitotic phosphoprotein) (EPS-15-interacting protein 1)
Gene: EPN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23187125
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005768 - endosome GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1356 Hs			1 576
+	Bt
		94410 F1MWF1_BOVIN (14-1254): 0: 942: 91.46		F1N579_BOVIN (1-576): 1.09e-92: 297: 92.91
+	Mm
		729409 VGFR3_MOUSE (28-1348): 0: 785: 42.85		EPN1_MOUSE (1-576): 1.93e-88: 286: 94.44
+	Mm
		729410 VGFR3_MOUSE (28-1348): 0: 785: 42.85		EPN2_MOUSE (1-562): 4.4e-64: 222: 41.91
+	Hs
		601512 FGFR2_HUMAN (1-231): 3.47e-24: 112: 9.57		EPN4_HUMAN (3-561): 1.44e-89: 290: 24.14
+	Hs
		508002 FGFR1_HUMAN (1-169): 8.34e-17: 88.1: 13.54		EPN4_HUMAN (3-561): 1.44e-89: 290: 24.14
+	Hs
		508299 FGFR1_HUMAN (1-169): 8.34e-17: 88.1: 13.54		EPN1_HUMAN (1-576): 4.42e-90: 290: 100.00
+	Hs
		607969 FGFR4_HUMAN (538-817): 2.68e-15: 83.5: 14.42		EPN4_HUMAN (3-561): 1.44e-89: 290: 24.14
+	Hs
		729401 VGFR3_HUMAN (1-123): 1.31e-13: 78.1: 14.93		EPN1_HUMAN (1-576): 4.42e-90: 290: 100.00
+	Hs
		307502 FGFR1_HUMAN (1-169): 8.34e-17: 88.1: 13.54		EPN2_HUMAN (1-566): 6.51e-54: 195: 38.02
+	Hs
		307505 FGFR4_HUMAN (538-817): 2.68e-15: 83.5: 14.42		EPN2_HUMAN (1-566): 6.51e-54: 195: 38.02
+	Hs
		203204 FGFR1_HUMAN (1-169): 8.34e-17: 88.1: 13.54		SYNJ1_HUMAN (246-573): 8.14e-20: 96.3: 14.11