HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: TICRR (Q7Z2Z1)
Treslin (TopBP1-interacting checkpoint and replication regulator) (TopBP1-interacting, replication-stimulating protein)
Gene: TICRR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1910
+	Hs
		971704 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		TICRR_HUMAN (1-1910): 0: 981: 100.00
+	Hs
		990411 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TICRR_HUMAN (1-1910): 0: 981: 100.00
+	Hs
		691176 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		TICRR_HUMAN (1-1910): 0: 981: 100.00
+	Hs
		971678 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		OTOG_HUMAN (1332-1884): 1.35e-26: 121: 12.19
+	Hs
		729976 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		OTOG_HUMAN (1332-1884): 1.35e-26: 121: 12.19
+	Hs
		990385 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		OTOG_HUMAN (1332-1884): 1.35e-26: 121: 12.19
+	Hs
		990225 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MDC1_HUMAN (702-1902): 4.04e-25: 116: 10.30
+	Hs
		274129 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		ANR17_HUMAN (831-1465): 2.52e-15: 84.6: 13.89
+	Hs
		274105 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		ANR17_HUMAN (831-1465): 2.52e-15: 84.6: 13.89
+	Hs
		730259 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		TENS1_HUMAN (1020-1901): 4.17e-15: 83.8: 10.77
+	Hs
		319058 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		K0754_HUMAN (538-1048): 1.31e-13: 79.2: 8.58
+	Hs
		319052 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		K0754_HUMAN (538-1048): 1.31e-13: 79.2: 8.58
+	Hs
		274131 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		ANR17_HUMAN (831-1465): 2.52e-15: 84.6: 13.89
+	Hs
		691153 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		OTOG_HUMAN (1332-1884): 1.35e-26: 121: 12.19
+	Hs
		990757 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TENS1_HUMAN (1020-1901): 4.17e-15: 83.8: 10.77
+	Hs
		319061 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		K0754_HUMAN (538-1048): 1.31e-13: 79.2: 8.58
+	Hs
		990550 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TITIN_HUMAN (896-1854): 2.44e-10: 68.4: 7.80
+	Hs
		274099 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		ANR17_HUMAN (831-1465): 2.52e-15: 84.6: 13.89
+	Hs
		691449 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		TENS1_HUMAN (1020-1901): 4.17e-15: 83.8: 10.77
+	Hs
		691291 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		TITIN_HUMAN (896-1854): 2.44e-10: 68.4: 7.80