HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: TENS1 (Q9HBL0)
Tensin-1 (EC 3.1.3.-)
Gene: TNS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	14-3-3~C1_1
Common GO terms	GO:0005737 - cytoplasm GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1839
+	Hs
		990757 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TENS1_HUMAN (1-1839): 0: 879: 100.00
+	Hs
		691449 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		TENS1_HUMAN (1-1839): 0: 879: 100.00
+	Mm
		147750 1433E_MOUSE (3-243): 4.41e-144: 405: 65.43		PTEN_MOUSE (116-486): 7.16e-114: 369: 27.21
+	Hs
		729933 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		TENS3_HUMAN (718-1838): 1.33e-96: 346: 26.42
+	Dm
		709541 1433Z_DROME (2-246): 4.81e-141: 396: 78.78		Q7KMQ6_DROME (111-477): 8.97e-99: 330: 26.17
+	Hs
		691117 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		TENS3_HUMAN (718-1838): 1.33e-96: 346: 26.42
+	Hs
		971632 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		TENS2_HUMAN (854-1837): 3.29e-72: 269: 25.83
+	Hs
		729931 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		TENS2_HUMAN (854-1837): 3.29e-72: 269: 25.83
+	Hs
		966457 1433G_HUMAN (3-246): 1.92e-109: 317: 75.40		TENS3_HUMAN (718-1838): 1.33e-96: 346: 26.42
+	Hs
		691114 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		TENS2_HUMAN (854-1837): 3.29e-72: 269: 25.83
+	Hs
		966453 1433G_HUMAN (3-246): 1.92e-109: 317: 75.40		TENS2_HUMAN (854-1837): 3.29e-72: 269: 25.83
+	Hs
		668549 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		APC_HUMAN (360-1497): 1.17e-35: 151: 9.59
+	Hs
		668512 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		APC_HUMAN (360-1497): 1.17e-35: 151: 9.59
+	Hs
		668551 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		APC_HUMAN (360-1497): 1.17e-35: 151: 9.59
+	Hs
		668509 1433T_HUMAN (3-244): 3.25e-127: 361: 81.82		APC_HUMAN (360-1497): 1.17e-35: 151: 9.59
+	Hs
		319058 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		K0754_HUMAN (1027-1555): 1.15e-16: 89: 13.21
+	Hs
		319052 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		K0754_HUMAN (1027-1555): 1.15e-16: 89: 13.21
+	Hs
		319061 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		K0754_HUMAN (1027-1555): 1.15e-16: 89: 13.21
+	Hs
		668547 1433G_HUMAN (3-246): 1.92e-109: 317: 75.40		APC_HUMAN (360-1497): 1.17e-35: 151: 9.59
+	Hs
		668564 1433F_HUMAN (4-244): 2.72e-107: 311: 75.51		APC_HUMAN (360-1497): 1.17e-35: 151: 9.59