HitPredict

Interactor 1: YPT53 (P36019)
GTP-binding protein YPT53
Gene: YPT53

Interactor 2: GDI1 (P39958)
Rab GDP-dissociation inhibitor (Rab GDI) (Secretory pathway GDP dissociation inhibitor)
Gene: GDI1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.80	0.687

Property	Details
Experiments	11785952, 22157956
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 220 Sc			1 451
+	Sc
		350882 YPT1_YEAST (10-218): 2.04e-87: 258: 29.67		GDI1_YEAST (1-451): 0: 667: 100.00
+	Sc
		731176 VPS21_YEAST (12-220): 3.21e-87: 258: 56.94		GDI1_YEAST (1-451): 0: 667: 100.00
+	Hs
		678333 RAB13_HUMAN (6-208): 1.6e-87: 258: 31.03		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		838608 RAB13_HUMAN (6-208): 1.6e-87: 258: 31.03		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Mm
		838709 RAB1A_MOUSE (1-218): 9.59e-80: 239: 30.73		GDIA_MOUSE (6-450): 0: 653: 54.04
+	Hs
		678344 RAB1A_HUMAN (1-218): 9.59e-80: 239: 30.73		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		838625 RAB1A_HUMAN (1-218): 9.59e-80: 239: 30.73		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Hs
		678343 RB11A_HUMAN (1-219): 4.39e-79: 237: 32.58		GDIA_HUMAN (6-450): 0: 652: 53.81
+	Hs
		838624 RB11A_HUMAN (1-219): 4.39e-79: 237: 32.58		GDIB_HUMAN (6-450): 0: 651: 54.04
+	Dm
		185501 O18332_DROME (1-218): 9.11e-79: 236: 29.82		Q9VLB7_DROME (6-448): 0: 625: 53.38
+	Sc
		699421 YPT53_YEAST (1-220): 9.57e-92: 269: 100.00		RAEP_YEAST (5-385): 5.77e-114: 348: 25.30
+	Sc
		350859 YPT1_YEAST (10-218): 2.04e-87: 258: 29.67		RAEP_YEAST (5-385): 5.77e-114: 348: 25.30
+	Sc
		699419 VPS21_YEAST (12-220): 3.21e-87: 258: 56.94		RAEP_YEAST (5-385): 5.77e-114: 348: 25.30
+	At
		1228189 RAA1D_ARATH (4-219): 3.23e-85: 253: 31.48		REP_ARATH (3-444): 1.06e-107: 331: 21.67
+	At
		656917 RAE1C_ARATH (8-219): 9.31e-80: 239: 33.96		REP_ARATH (3-444): 1.06e-107: 331: 21.67
+	Hs
		622577 RAB1A_HUMAN (1-218): 9.59e-80: 239: 30.73		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		642723 RAB1A_HUMAN (1-218): 9.59e-80: 239: 30.73		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71
+	Hs
		622576 RB11A_HUMAN (1-219): 4.39e-79: 237: 32.58		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68
+	Hs
		642722 RB11A_HUMAN (1-219): 4.39e-79: 237: 32.58		RAE2_HUMAN (4-73): 2.02e-15: 80.4: 35.71
+	Hs
		622619 RAB1B_HUMAN (7-218): 2.87e-78: 235: 31.13		RAE1_HUMAN (4-62): 1.22e-15: 81.2: 40.68