Interactor 1: DYHC (P36022)
Dynein heavy chain, cytoplasmic (Dynein heavy chain, cytosolic) (DYHC)
Gene: DYN1

Interactor 2: LIS1 (P39946)
Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog)
Gene: PAC1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.961

The method score is based on:

Property Details
Experiments 28886386, 34994688, 37620585, 22875988, 37322240, 37919547, 24916158
Identification Methods pull down, x-ray crystallography, two hybrid
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_8~WD40, AAA_9~WD40, DHC_N1~WD40
Common GO terms GO:0000132 - establishment of mitotic spindle orientation
GO:0005737 - cytoplasm
GO:0005881 - cytoplasmic microtubule
GO:0007097 - nuclear migration
GO:0008090 - retrograde axonal transport
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 4092
Sc

1 494
+ Mm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024