HitPredict

Interactor 1: B4DYC6 (B4DYC6)
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1 (SUGT1), mRNA
Gene: B4DYC6

Interactor 2: Q6PK50 (Q6PK50)
Heat shock protein HSP 90-beta
Gene: HSP90AB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 277 Hs			1 351
+	Hs
		438644 SGT1_HUMAN (1-277): 1.32e-130: 376: 87.06		HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00
+	Hs
		432387 SGT1_HUMAN (1-277): 1.32e-130: 376: 87.06		HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92
+	At
		646596 SGT1A_ARATH (2-277): 1.02e-123: 358: 36.67		HS901_ARATH (10-349): 1.34e-158: 462: 67.45
+	At
		646597 SGT1B_ARATH (2-277): 1.2e-119: 348: 36.36		HS901_ARATH (10-349): 1.34e-158: 462: 67.45
+	At
		878286 SGT1B_ARATH (2-277): 1.2e-119: 348: 36.36		HS902_ARATH (10-349): 1.58e-158: 462: 67.45
+	Hs
		538450 SGT1_HUMAN (1-277): 1.32e-130: 376: 87.06		ENPL_HUMAN (2-351): 6.06e-139: 415: 42.54
+	Ce
		1090253 Q18949_CAEEL (81-277): 2.39e-68: 211: 34.50		HSP90_CAEEL (8-350): 3.89e-156: 456: 71.14
+	Hs
		301352 UBP19_HUMAN (67-222): 3.2e-37: 141: 19.65		HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00
+	Hs
		301408 UBP19_HUMAN (67-222): 3.2e-37: 141: 19.65		Q6PK50_HUMAN (1-345): 2.04e-180: 505: 100.00
+	Hs
		301351 UBP19_HUMAN (67-222): 3.2e-37: 141: 19.65		HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92
+	Mm
		513702 CHRD1_MOUSE (73-182): 1.16e-35: 131: 23.64		HS90B_MOUSE (1-345): 1.63e-176: 509: 99.71
+	Hs
		438592 CHRD1_HUMAN (73-185): 3.8e-36: 133: 23.89		HS90B_HUMAN (1-345): 1.2e-175: 506: 100.00
+	Hs
		111942 CHRD1_HUMAN (73-185): 3.8e-36: 133: 23.89		K9JA46_HUMAN (1-350): 1.31e-173: 501: 84.92
+	Hs
		432333 CHRD1_HUMAN (73-185): 3.8e-36: 133: 23.89		HS90A_HUMAN (1-350): 1.31e-173: 501: 84.92
+	Pf
		83109 C0H586_PLAF7 (84-265): 1.64e-57: 184: 30.60		Q8IC05_PLAF7 (11-350): 6.38e-153: 449: 62.77
+	Mm
		432455 CHRD1_MOUSE (73-182): 1.16e-35: 131: 23.64		HS90A_MOUSE (1-350): 2.76e-173: 501: 84.12
+	Sc
		367015 SGT1_YEAST (77-277): 3.65e-59: 194: 33.04		HSP82_YEAST (11-350): 7.63e-148: 435: 66.86
+	Sc
		544530 SGT1_YEAST (77-277): 3.65e-59: 194: 33.04		HSC82_YEAST (13-350): 9.86e-147: 432: 65.19
+	Dm
		365474 CHRD1_DROME (61-205): 6.7e-36: 132: 22.30		HSP83_DROME (8-350): 1.73e-170: 493: 79.88
+	Hs
		1197923 CHRD1_HUMAN (73-185): 3.8e-36: 133: 23.89		Q86SX1_HUMAN (1-135): 3.65e-78: 242: 88.57