HitPredict

Interactor 1: DOA1 (P36037)
Protein DOA1 (Degradation of alpha protein 1) (Ubiquitin fusion degradation protein 3)
Gene: DOA1

Interactor 2: HSE1 (P38753)
Class E vacuolar protein-sorting machinery protein HSE1
Gene: HSE1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.707

Property	Details
Experiments	11743162, 18508771, 19841731, 24607902
Identification Methods	two hybrid, affinity chromatography technology, pull down, x-ray crystallography, two hybrid array, two hybrid pooling approach
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010008 - endosome membrane GO:0043130 - ubiquitin binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 715 Sc			1 452
+	Sc
		744613 TAF5_YEAST (89-302): 5.91e-19: 93.6: 32.74		GGA2_YEAST (6-441): 1.14e-41: 158: 13.60
+	Hs
		1288351 SNR40_HUMAN (4-83): 2.88e-13: 73.9: 15.29		ITSN2_HUMAN (196-273): 2.11e-11: 68.4: 30.86
+	Hs
		61736 SNR40_HUMAN (4-83): 2.88e-13: 73.9: 15.29		A6H8W8_HUMAN (196-273): 2.46e-11: 68.4: 30.86