HitPredict

Interactor 1: PDIA6 (Q15084)
Protein disulfide-isomerase A6 (EC 5.3.4.1) (Endoplasmic reticulum protein 5) (ER protein 5) (ERp5) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7)
Gene: PDIA6

Interactor 2: PTPRN (Q16849)
Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3) (PTP IA-2) [Cleaved into: ICA512-N-terminal fragment (ICA512-NTF); ICA512-transmembrane fragment (ICA512-TMF); ICA512-cleaved cytosolic fragment (ICA512-CCF)]
Gene: PTPRN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27880917, 27432908
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 979
+	Hs
		1088210 TXND5_HUMAN (177-431): 3.21e-41: 153: 20.37		PTPRN_HUMAN (29-979): 0: 753: 100.00
+	Hs
		531847 PDIA4_HUMAN (67-271): 1.28e-17: 87.3: 22.28		PTPRN_HUMAN (29-979): 0: 753: 100.00
+	Hs
		423244 PDIA1_HUMAN (62-387): 6.18e-10: 63: 11.59		PTPRN_HUMAN (29-979): 0: 753: 100.00
+	Hs
		671826 PDIA3_HUMAN (13-386): 9.31e-10: 62.6: 11.02		PTPRN_HUMAN (29-979): 0: 753: 100.00
+	Hs
		577022 PDIA6_HUMAN (1-440): 1.21e-134: 396: 100.00		PTPRA_HUMAN (217-970): 1.14e-111: 365: 17.77
+	Hs
		660849 PDIA6_HUMAN (1-440): 1.21e-134: 396: 100.00		PTPRM_HUMAN (678-973): 7.59e-61: 228: 28.95
+	Hs
		1067777 PDIA6_HUMAN (1-440): 1.21e-134: 396: 100.00		PTPRU_HUMAN (683-976): 3.8e-59: 223: 28.71
+	Hs
		1087926 TMX3_HUMAN (3-127): 8.56e-18: 87: 35.94		PTN21_HUMAN (49-972): 3.43e-157: 496: 15.85
+	Hs
		577042 TXND5_HUMAN (177-431): 3.21e-41: 153: 20.37		PTPRA_HUMAN (217-970): 1.14e-111: 365: 17.77
+	Hs
		423236 PDIA1_HUMAN (62-387): 6.18e-10: 63: 11.59		PTPRR_HUMAN (533-966): 1.18e-124: 395: 21.80
+	Hs
		423138 PDIA1_HUMAN (62-387): 6.18e-10: 63: 11.59		PTN1_HUMAN (698-974): 4.8e-118: 370: 35.76
+	Hs
		660862 DJC10_HUMAN (119-381): 3.95e-19: 92.3: 20.68		PTPRM_HUMAN (678-973): 7.59e-61: 228: 28.95
+	Hs
		1220443 DJC10_HUMAN (119-381): 3.95e-19: 92.3: 20.68		PTPRU_HUMAN (683-976): 3.8e-59: 223: 28.71
+	Hs
		570556 TXND5_HUMAN (177-431): 3.21e-41: 153: 20.37		PTN2_HUMAN (734-973): 7.83e-42: 160: 38.21
+	Hs
		531930 PDIA4_HUMAN (67-271): 1.28e-17: 87.3: 22.28		PTPRU_HUMAN (683-976): 3.8e-59: 223: 28.71
+	Hs
		423314 PDIA1_HUMAN (62-387): 6.18e-10: 63: 11.59		PTPRU_HUMAN (683-976): 3.8e-59: 223: 28.71
+	Hs
		671887 PDIA3_HUMAN (13-386): 9.31e-10: 62.6: 11.02		PTPRU_HUMAN (683-976): 3.8e-59: 223: 28.71
+	Hs
		570550 DJC10_HUMAN (119-381): 3.95e-19: 92.3: 20.68		PTN2_HUMAN (734-973): 7.83e-42: 160: 38.21