HitPredict

Interactor 1: SN114 (P36048)
Pre-mRNA-splicing factor SNU114 (114 kDa U5 small nuclear ribonucleoprotein component) (Growth inhibitory protein 10)
Gene: SNU114

Interactor 2: LSM3 (P57743)
U6 snRNA-associated Sm-like protein LSm3 (SmX4 protein)
Gene: LSM3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.938

Property	Details
Experiments	10747033, 16554755, 19740761, 37968396, 14759368, 16429126
Identification Methods	biochemical, affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GTP_EFTU~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0005737 - cytoplasm GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1008 Sc			1 89
+	Hs
		927954 U5S1_HUMAN (2-1007): 0: 898: 31.43		RSMN_HUMAN (10-86): 1.36e-24: 93.7: 26.51
+	Hs
		538964 U5S1_HUMAN (2-1007): 0: 898: 31.43		RSMB_HUMAN (10-86): 3.53e-24: 92.9: 26.51
+	Hs
		1064819 U5S1_HUMAN (2-1007): 0: 898: 31.43		LSM7_HUMAN (2-85): 7.35e-25: 91: 30.59
+	Hs
		321402 U5S1_HUMAN (2-1007): 0: 898: 31.43		LSM8_HUMAN (6-89): 7.16e-22: 82.9: 23.81
+	Sc
		731738 SN114_YEAST (1-1008): 0: 895: 100.00		LSM1_YEAST (8-84): 1.39e-21: 84.5: 29.87
+	Hs
		912461 U5S1_HUMAN (2-1007): 0: 898: 31.43		SMD2_HUMAN (4-76): 1.47e-20: 80.2: 28.05
+	Hs
		912044 U5S1_HUMAN (2-1007): 0: 898: 31.43		RUXG_HUMAN (8-81): 2.24e-20: 78.7: 27.03
+	Sc
		731750 SN114_YEAST (1-1008): 0: 895: 100.00		LSM7_YEAST (2-83): 1.07e-20: 80.6: 30.23
+	Sc
		731773 SN114_YEAST (1-1008): 0: 895: 100.00		SMD2_YEAST (4-76): 1.35e-20: 80.2: 30.67
+	Sc
		731730 SN114_YEAST (1-1008): 0: 895: 100.00		LSM5_YEAST (4-83): 2.79e-19: 76.4: 24.69
+	Sp
		292950 SN114_SCHPO (1-1007): 0: 841: 32.82		RSMB_SCHPO (12-86): 7.35e-21: 81.8: 28.05
+	Sp
		144202 SN114_SCHPO (1-1007): 0: 841: 32.82		SMD2_SCHPO (4-77): 3.86e-19: 76.8: 26.83
+	Zm
		5855 A0A1D6E4M0_MAIZE (131-958): 0: 560: 17.65		B4FMM6_MAIZE (3-76): 4.35e-09: 50: 32.43
+	Sc
		810526 RIA1_YEAST (117-482): 3.67e-102: 347: 22.01		LSM1_YEAST (8-84): 1.39e-21: 84.5: 29.87