HitPredict

Interactor 1: TRI23 (P36406)
E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23)
Gene: TRIM23

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 16189514, 31515488, 29892012
Identification Methods two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-B_box~zf-C3HC4
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0016567 - protein ubiquitination
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 574
Hs

1 728
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024