Interactor 1: ARP3 (P32392)
Actin-related protein 3 (Actin-2) (Actin-like protein 3) (Actin-like protein 66B)
Gene: ARP3

Interactor 2: ARP2 (P45888)
Actin-related protein 2 (Actin-like protein 14D) (Actin-like protein 2)
Gene: ARP2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.797

The method score is based on:

Property Details
Experiments 22036573, 38944040, unassigned4
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, experimental interaction detection
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Actin
Common GO terms GO:0003779 - actin binding
GO:0005200 - structural constituent of cytoskeleton
GO:0005524 - ATP binding
GO:0005885 - Arp2/3 protein complex
GO:0030032 - lamellipodium assembly
and 4 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 418
Dm

1 399
+ Bt
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Gg
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025