HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 35575683, 38334954
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Actin
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0005884 - actin filament
and 5 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 375
Hs

1 377
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Service provided by Combinatics, Japan

Last updated: 11Aug2025