HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30344098
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016607 - nuclear speck
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 494
+	Hs
		737766 PP1G_HUMAN (1-323): 0: 603: 100.00		SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42
+	Hs
		737783 PP1G_HUMAN (1-323): 0: 603: 100.00		SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50
+	Hs
		737782 PP1G_HUMAN (1-323): 0: 603: 100.00		SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85
+	Hs
		516386 PP1G_HUMAN (1-323): 0: 603: 100.00		PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50
+	Hs
		516441 PP1A_HUMAN (1-323): 0: 579: 90.66		PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50
+	Hs
		737785 PP1G_HUMAN (1-323): 0: 603: 100.00		PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78
+	Hs
		905870 PP1A_HUMAN (1-323): 0: 579: 90.66		PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78
+	Hs
		516454 PP2AA_HUMAN (8-312): 5.65e-178: 496: 46.08		PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50
+	Mm
		857299 PP1B_MOUSE (1-322): 0: 560: 86.89		TIA1_MOUSE (98-188): 7.57e-10: 62.7: 17.02
+	Sp
		532280 PP11_SCHPO (7-322): 0: 555: 82.92		PABP_SCHPO (85-188): 6.14e-11: 66.9: 16.51
+	Zm
		6224 B4FJL0_MAIZE (4-314): 0: 550: 75.24		A0A1D6E6L1_MAIZE (106-186): 2.82e-11: 67.7: 26.74