HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: PPR3A (Q16821)
Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit) (RG1)
Gene: PPP1R3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	15016827
Identification Methods	pull down, far western blotting
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005977 - glycogen metabolic process GO:0008157 - protein phosphatase 1 binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 323 Hs			1 1122
+	Hs
		905933 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR3A_HUMAN (1-1122): 0: 1725: 100.00
+	Hs
		906477 PP1B_HUMAN (1-322): 0: 560: 86.89		PPR3A_HUMAN (1-1122): 0: 1725: 100.00
+	Mm
		906352 PP1A_MOUSE (1-323): 0: 579: 90.36		PPR3A_MOUSE (1-1122): 0: 1577: 61.31
+	Hs
		738131 PP1G_HUMAN (1-323): 0: 603: 100.00		PPR3C_HUMAN (32-283): 3.84e-93: 302: 26.59
+	Hs
		906203 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR3C_HUMAN (32-283): 3.84e-93: 302: 26.59
+	Hs
		906639 PP1B_HUMAN (1-322): 0: 560: 86.89		PPR3C_HUMAN (32-283): 3.84e-93: 302: 26.59
+	Hs
		319090 PP1G_HUMAN (1-323): 0: 603: 100.00		PPR3D_HUMAN (38-234): 7.09e-77: 257: 27.40
+	Hs
		737903 PP1G_HUMAN (1-323): 0: 603: 100.00		PPR3B_HUMAN (29-283): 9.27e-75: 250: 25.37
+	Hs
		319093 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR3D_HUMAN (38-234): 7.09e-77: 257: 27.40
+	Hs
		906001 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR3B_HUMAN (29-283): 9.27e-75: 250: 25.37
+	Mm
		57204 PP1A_MOUSE (1-323): 0: 579: 90.36		A2AJW4_MOUSE (38-234): 5.12e-69: 234: 26.44
+	Hs
		906518 PP1B_HUMAN (1-322): 0: 560: 86.89		PPR3B_HUMAN (29-283): 9.27e-75: 250: 25.37
+	Dm
		819235 PP11_DROME (5-323): 0: 569: 88.92		Q9VUF3_DROME (39-283): 3.86e-65: 227: 24.13
+	Dm
		819218 PP11_DROME (5-323): 0: 569: 88.92		Q8SWT8_DROME (39-283): 1.16e-65: 226: 24.13
+	Ce
		109596 GLC7B_CAEEL (3-323): 0: 584: 89.63		H2KYT5_CAEEL (49-240): 1.4e-57: 205: 25.49
+	Ce
		821923 GLC7B_CAEEL (3-323): 0: 584: 89.63		Q400N3_CAEEL (49-240): 1.93e-57: 204: 25.49
+	Dm
		819280 PP1B_DROME (1-323): 0: 552: 82.48		Q8SWT8_DROME (39-283): 1.16e-65: 226: 24.13
+	Dm
		819236 PP11_DROME (5-323): 0: 569: 88.92		GBS76_DROME (38-269): 3.35e-53: 200: 28.51
+	Hs
		81860 PP1A_HUMAN (1-323): 0: 579: 90.66		PP13G_HUMAN (45-229): 6.09e-52: 188: 26.14
+	Hs
		906138 PP1A_HUMAN (1-323): 0: 579: 90.66		PPR3E_HUMAN (41-247): 3.43e-52: 186: 24.32