Interactor 1: UBC12 (P61081)
NEDD8-conjugating enzyme Ubc12 (EC 2.3.2.34) (NEDD8 carrier protein) (Ubiquitin-conjugating enzyme E2 M)
Gene: UBE2M
Interactor 2: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.982 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442, 28581483, 30804002, 33961781, 34642328, 16620772, 16503656, 21765416, 18264111, 25416956, 17353931, 35271311, 21145461, 19713960, 18274552 |
| Identification Methods | affinity chromatography technology, enzymatic study, pull down, comigration in sds page, mammalian protein protein interaction trap, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | UQ_con~ubiquitin |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0036211 - protein modification process GO:0045116 - protein neddylation |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
