HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: SFRP1 (Q8N474)
Secreted frizzled-related protein 1 (FRP-1) (sFRP-1) (Secreted apoptosis-related protein 2) (SARP-2)
Gene: SFRP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.649

Property	Details
Experiments	17123353, 21382349
Identification Methods	two hybrid, pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 314
+	Hs
		906019 PP1A_HUMAN (1-323): 0: 579: 90.66		SFRP1_HUMAN (1-314): 3.07e-124: 359: 100.00
+	Hs
		906532 PP1B_HUMAN (1-322): 0: 560: 86.89		SFRP1_HUMAN (1-314): 3.07e-124: 359: 100.00
+	Hs
		737855 PP1G_HUMAN (1-323): 0: 603: 100.00		SFRP5_HUMAN (29-313): 4.32e-105: 311: 55.75
+	Hs
		905956 PP1A_HUMAN (1-323): 0: 579: 90.66		SFRP5_HUMAN (29-313): 4.32e-105: 311: 55.75
+	Hs
		737974 PP1G_HUMAN (1-323): 0: 603: 100.00		SFRP2_HUMAN (51-306): 4.51e-93: 280: 42.59
+	Hs
		906488 PP1B_HUMAN (1-322): 0: 560: 86.89		SFRP5_HUMAN (29-313): 4.32e-105: 311: 55.75
+	Hs
		906078 PP1A_HUMAN (1-323): 0: 579: 90.66		SFRP2_HUMAN (51-306): 4.51e-93: 280: 42.59
+	Hs
		906559 PP1B_HUMAN (1-322): 0: 560: 86.89		SFRP2_HUMAN (51-306): 4.51e-93: 280: 42.59