HitPredict

Interactor 1: NHP2 (P32495)
H/ACA ribonucleoprotein complex subunit NHP2 (H/ACA snoRNP protein NHP2) (High mobility group-like nuclear protein 2)
Gene: NHP2

Interactor 2: NOP10 (Q6Q547)
H/ACA ribonucleoprotein complex subunit NOP10 (Nucleolar protein 10) (Nucleolar protein family A member 3) (snoRNP protein NOP10)
Gene: NOP10

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.920

The method score is based on:

Property Details
Experiments 18719252, 16554755, 37968396, 31851481, 22085967
Identification Methods two hybrid, affinity chromatography technology, cross-linking study, pull down, tandem affinity purification
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Nop10p~Ribosomal_L7Ae
Common GO terms GO:0000454 - snoRNA guided rRNA pseudouridine synthesis
GO:0005730 - nucleolus
GO:0005732 - sno(s)RNA-containing ribonucleoprotein complex
GO:0006364 - rRNA processing
GO:0031118 - rRNA pseudouridine synthesis
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 156
Sc

1 58
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 11Aug2025