HitPredict

Interactor 1: RPN12 (P32496)
26S proteasome regulatory subunit RPN12 (Nuclear integrity protein 1)
Gene: RPN12

Interactor 2: RPN2 (P32565)
26S proteasome regulatory subunit RPN2
Gene: RPN2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

Property	Details
Experiments	16429126, 37968396, 31848235, 15572408, 16554755, 22940862
Identification Methods	affinity chromatography technology, cross-linking study, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process GO:0034515 - proteasome storage granule GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 274 Sc			1 945
+	Sp
		268021 RPN12_SCHPO (11-274): 3.45e-91: 272: 30.91		RPN2_SCHPO (3-938): 0: 1002: 41.56
+	Dm
		1464087 Q9V436_DROME (1-274): 2.48e-78: 239: 26.72		PSMD1_DROME (1-927): 0: 990: 36.04
+	Hs
		874150 PSMD8_HUMAN (16-274): 3.1e-101: 300: 31.27		PSMD2_HUMAN (9-770): 0: 760: 17.31
+	At
		1456452 PSD8A_ARATH (2-274): 3.1e-93: 277: 28.06		PSD2A_ARATH (9-770): 0: 669: 17.76
+	Sp
		896089 RPN12_SCHPO (11-274): 3.45e-91: 272: 30.91		RPN1_SCHPO (9-770): 0: 621: 18.33
+	Dm
		1465242 Q9V436_DROME (1-274): 2.48e-78: 239: 26.72		Q9VW54_DROME (13-770): 0: 651: 17.61
+	Sc
		738304 RPN12_YEAST (1-274): 3.73e-102: 300: 100.00		RPN1_YEAST (9-573): 1.14e-134: 430: 17.33