HitPredict

Interactor 1: FLT3 (P36888)
Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)
Gene: FLT3

Interactor 2: SAR1B (Q9Y6B6)
Small COPII coat GTPase SAR1B (EC 3.6.5.2) (GTP-binding protein B) (GTBPB) (Secretion-associated Ras-related GTPase 1B)
Gene: SAR1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 993 Hs			1 198
+	Hs
		574613 FLT3_HUMAN (1-993): 0: 844: 97.89		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		738190 FLT3_HUMAN (1-993): 0: 844: 97.89		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Hs
		572582 VGFR1_HUMAN (74-537): 1.47e-36: 152: 14.31		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		572614 VGFR1_HUMAN (74-537): 1.47e-36: 152: 14.31		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Hs
		572686 VGFR1_HUMAN (74-537): 1.47e-36: 152: 14.31		SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90
+	Hs
		574612 VGFR3_HUMAN (70-533): 8.45e-27: 120: 14.15		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		729257 VGFR3_HUMAN (70-533): 8.45e-27: 120: 14.15		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Hs
		601491 FGFR2_HUMAN (8-273): 1.07e-26: 119: 11.69		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Hs
		507840 FGFR1_HUMAN (6-360): 2.83e-24: 111: 10.90		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		574596 FGFR3_HUMAN (20-260): 5.2e-21: 101: 9.09		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		729366 VGFR3_HUMAN (70-533): 8.45e-27: 120: 14.15		SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90
+	Hs
		574595 FGFR4_HUMAN (47-355): 1.59e-17: 89.8: 11.67		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		729399 VGFR3_HUMAN (70-533): 8.45e-27: 120: 14.15		SAR1B_HUMAN (1-198): 3.26e-59: 185: 100.00
+	Hs
		507936 FGFR1_HUMAN (6-360): 2.83e-24: 111: 10.90		RAB1A_HUMAN (18-197): 7.2e-62: 192: 19.46
+	Hs
		609559 FGFR3_HUMAN (20-260): 5.2e-21: 101: 9.09		SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90
+	Hs
		452347 PGFRB_HUMAN (16-230): 1.69e-09: 64: 15.04		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66