HitPredict

Interactor 1: TGFR2 (P37173)
TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II)
Gene: TGFBR2

Interactor 2: MARH7 (Q9H992)
E3 ubiquitin-protein ligase MARCHF7 (EC 2.3.2.27) (Axotrophin) (Membrane-associated RING finger protein 7) (Membrane-associated RING-CH protein VII) (MARCH-VII) (RING finger protein 177) (RING-type E3 ubiquitin transferase MARCHF7)
Gene: MARCHF7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.712

Property	Details
Experiments	29794480, 26186194, 28514442, 33961781, 34591642
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 567 Hs			1 704
+	Hs
		1044943 AVR2B_HUMAN (69-565): 5.95e-135: 404: 33.79		MARH7_HUMAN (1-704): 0: 942: 100.00
+	Hs
		740021 TGFR2_HUMAN (1-567): 1.25e-149: 443: 100.00		MARH1_HUMAN (490-647): 1.35e-47: 171: 22.15
+	Hs
		646075 AVR2A_HUMAN (37-549): 8.74e-128: 385: 32.83		MARH2_HUMAN (490-681): 5.49e-52: 182: 19.60
+	Hs
		646053 AVR2A_HUMAN (37-549): 8.74e-128: 385: 32.83		MARH1_HUMAN (490-647): 1.35e-47: 171: 22.15
+	Hs
		1046379 BMPR2_HUMAN (25-567): 5e-117: 372: 28.34		MARH1_HUMAN (490-647): 1.35e-47: 171: 22.15
+	Hs
		1044949 AVR2B_HUMAN (69-565): 5.95e-135: 404: 33.79		MARH4_HUMAN (538-647): 2.16e-27: 117: 22.52
+	Hs
		738383 BMR1A_HUMAN (61-548): 6.88e-114: 350: 26.68		MARH1_HUMAN (490-647): 1.35e-47: 171: 22.15
+	Hs
		738421 BMR1A_HUMAN (61-548): 6.88e-114: 350: 26.68		MARH4_HUMAN (538-647): 2.16e-27: 117: 22.52