HitPredict

Interactor 1: VPP2 (P37296)
V-type proton ATPase subunit a, Golgi isoform (V-ATPase a 2 subunit) (Similar to VPH1 protein 1) (V-ATPase 101 kDa subunit) (V-ATPase subunit AC115) (Vacuolar proton translocating ATPase subunit a 2)
Gene: STV1

Interactor 2: VATH (P41807)
V-type proton ATPase subunit H (V-ATPase subunit H) (V-ATPase 54 kDa subunit) (Vacuolar proton pump subunit H)
Gene: VMA13

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 11592965, 18467557, 28183979
Identification Methods coimmunoprecipitation, affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains V-ATPase_H_C~V_ATPase_I, V-ATPase_H_N~V_ATPase_I
Common GO terms GO:0000139 - Golgi membrane
GO:0000329 - fungal-type vacuole membrane
GO:0007035 - vacuolar acidification
GO:0016471 - vacuolar proton-transporting V-type ATPase complex
GO:0033176 - proton-transporting V-type ATPase complex
and 4 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 890
Sc

1 478
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024