HitPredict

Interactor 1: MAK5 (P38112)
ATP-dependent RNA helicase MAK5 (EC 3.6.4.13) (Maintenance of killer protein 5)
Gene: MAK5

Interactor 2: PESC (P53261)
Pescadillo homolog (Nucleolar protein 7) (Ribosomal RNA-processing protein 13)
Gene: NOP7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	16554755, 30568249
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 773 Sc			1 605
+	Sc
		624138 DBP2_YEAST (62-611): 3.49e-122: 379: 21.62		PESC_YEAST (1-605): 0: 702: 100.00
+	Hs
		132048 DDX3X_HUMAN (28-618): 9.99e-129: 400: 20.92		PESC_HUMAN (4-599): 0: 667: 37.40
+	Sc
		699706 DRS1_YEAST (174-666): 9.19e-41: 162: 29.06		PESC_YEAST (1-605): 0: 702: 100.00
+	Sc
		860870 HAS1_YEAST (178-598): 2.55e-41: 160: 31.46		PESC_YEAST (1-605): 0: 702: 100.00
+	Hs
		132192 DDX27_HUMAN (57-587): 1.9e-39: 158: 28.55		PESC_HUMAN (4-599): 0: 667: 37.40
+	Hs
		132227 DDX18_HUMAN (70-598): 3.25e-38: 153: 29.16		PESC_HUMAN (4-599): 0: 667: 37.40