HitPredict

Interactor 1: RBMX (P38159)
RNA-binding motif protein, X chromosome (Glycoprotein p43) (Heterogeneous nuclear ribonucleoprotein G) (hnRNP G) [Cleaved into: RNA-binding motif protein, X chromosome, N-terminally processed]
Gene: RBMX

Interactor 2: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21723381
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0048025 - negative regulation of mRNA splicing, via spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 391 Hs			1 494
+	Hs
		745151 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50
+	Hs
		745150 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53
+	Hs
		992876 RMXL1_HUMAN (1-358): 1.92e-39: 146: 95.25		SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42
+	Hs
		1029031 RMXL1_HUMAN (1-358): 1.92e-39: 146: 95.25		SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50
+	Hs
		993796 RMXL1_HUMAN (1-358): 1.92e-39: 146: 95.25		SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00
+	Hs
		1029160 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50
+	Hs
		1028634 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53
+	Hs
		993869 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00
+	Mm
		857340 TIA1_MOUSE (2-371): 3.45e-25: 107: 14.18		SRSF1_MOUSE (3-166): 2.36e-57: 192: 41.42
+	Hs
		992743 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42
+	Hs
		1028873 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85
+	Mm
		857324 TIA1_MOUSE (2-371): 3.45e-25: 107: 14.18		Q542V3_MOUSE (1-468): 2.02e-54: 191: 80.38
+	Hs
		516389 RBMX_HUMAN (1-367): 4.4e-45: 161: 100.00		PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50
+	Hs
		1020247 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50
+	Hs
		516744 PPIE_HUMAN (10-96): 1.5e-32: 126: 40.23		PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50
+	Hs
		516484 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50
+	Mm
		665745 TIA1_MOUSE (2-371): 3.45e-25: 107: 14.18		PABP1_MOUSE (1-189): 6.69e-31: 128: 19.50
+	Hs
		1020249 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78
+	Hs
		474019 ELAV2_HUMAN (10-91): 2.48e-25: 107: 29.27		PAB4L_HUMAN (100-185): 1.44e-10: 65: 19.78
+	Hs
		680422 TIA1_HUMAN (2-371): 9.39e-25: 106: 14.81		TIA1_HUMAN (98-188): 6.06e-10: 63.1: 17.02