HitPredict

Interactor 1: AGRE5 (P48960)
Adhesion G protein-coupled receptor E5 (Leukocyte antigen CD97) (CD antigen CD97) [Cleaved into: Adhesion G protein-coupled receptor E5 subunit alpha; Adhesion G protein-coupled receptor E5 subunit beta]
Gene: ADGRE5

Interactor 2: LPAR1 (Q92633)
Lysophosphatidic acid receptor 1 (LPA receptor 1) (LPA-1) (Lysophosphatidic acid receptor Edg-2)
Gene: LPAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004930 - G protein-coupled receptor activity GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 835 Hs			1 364
+	Hs
		328313 AGRE5_HUMAN (1-835): 0: 590: 100.00		S1PR4_HUMAN (1-360): 9.27e-72: 230: 30.89
+	Hs
		1268681 AGRE2_HUMAN (1-831): 4.31e-172: 519: 60.40		LPAR1_HUMAN (1-364): 3.44e-73: 233: 100.00
+	Hs
		1268659 AGRL3_HUMAN (315-835): 6.03e-134: 435: 31.29		LPAR1_HUMAN (1-364): 3.44e-73: 233: 100.00
+	Hs
		1197861 AGRG6_HUMAN (351-820): 1.28e-92: 318: 20.97		LPAR1_HUMAN (1-364): 3.44e-73: 233: 100.00
+	Hs
		429162 AGRG1_HUMAN (317-794): 4.12e-89: 298: 20.04		ADRB2_HUMAN (54-350): 1.7e-66: 217: 17.38
+	Hs
		600727 CRFR2_HUMAN (538-833): 1.56e-77: 259: 21.90		DRD1_HUMAN (66-363): 6.47e-59: 198: 17.73
+	Hs
		328394 CELR2_HUMAN (160-527): 1.61e-11: 70.8: 9.48		S1PR4_HUMAN (1-360): 9.27e-72: 230: 30.89